Radionuclide studies have made a major contribution to our understanding of the changes that the body undergoes in health and disease. Moore et al. (1963) used them to develop their concept of the body being made up of a number of distinguishable physiological compartments. First, the body cell mass, the ‘engine’, which comprises all the cells of the body, characteristically oxygen consuming and energy exchanging. Second, the extracellular tissues, the ‘chassis’, with a predominantly supporting role and characteristically very low metabolic activity. Third, the body fat, neutral triglyceride. Much of the extracellular compartment is fluid and includes the blood plasma, the interstitial fluid, cerebrospinal fluid, localized effusions and digestive juices.
KeywordsBody Composition Human Serum Albumin Total Body Water Extracellular Compartment Exchangeable Sodium
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