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Drugs for Heart Disease pp 349–363Cite as

The management of the hyperlipidaemias

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Abstract

The hyperlipidaemias are a common and heterogeneous group of metabolic disorders which affect more than 10% of the population of Western industrialized countries [1–3]. Although hypertension and diabetes mellitus are well established as predisposing factors for the development of atherosclerotic disease [4, 5] the role of dietary fat and altered lipoprotein metabolism is not so well understood [6–8]. Epidemiological studies have demonstrated that increased levels of plasma cholesterol may be associated with premature coronary heart disease [2, 3] and the United States Lipid Research Clinics trial [9] has given clear evidence that reducing high cholesterol levels in men will lower the incidence of coronary heart disease (CHD), and additionally will significantly reduce deaths, myocardial infarcts, angina and the need for coronary artery bypass surgery. These results confirm previous similar reports [10–12].

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Authors
  1. N. I. Jowett
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  2. D. J. Galton
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Editor information

Editors and Affiliations

  1. Formerly Consultant Cardiologist, now retired, Department of Clinical Pharmacology, St Bartholomew’s Hospital, EC1A 7BE, London, UK

    John Hamer MD. Ph.D F.R.C.P.

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© 1987 Springer Science+Business Media Dordrecht

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Jowett, N.I., Galton, D.J. (1987). The management of the hyperlipidaemias. In: Hamer, J. (eds) Drugs for Heart Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3294-5_12

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  • DOI: https://doi.org/10.1007/978-1-4899-3294-5_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-412-26540-2

  • Online ISBN: 978-1-4899-3294-5

  • eBook Packages: Springer Book Archive

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