Takayasu arteritis: a current update

  • J. T. Lie


Takayasu arteritis has many synonyms (Table 13.1), among them are aortic arch syndrome, pulseless disease, primary arteritis, non-specific aortoarteritis, idiopathic aortitis and occlusive thromboarteriopathy [1–25]. Of interest, it was probably an English surgeon, Savory, in 1856 [26], who first described the entity now known as Takayasu arteritis. Takayasu [27], a Japanese ophthalmologist, had merely reported ‘a case with peculiar changes of the central retinal vessels’ in a young woman who apparently had pulseless disease of which Takayasu was totally unaware, and he certainly did not describe an arteritis of the aorta or the aortic arch vessels then in 1908, or later.


Aortic Arch Abdominal Aorta Giant Cell Arteritis Takayasu Arteritis Pulseless Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Beneke, R. (1925) Ein eigentümlicher Fall schwieliger Aortitis. Virchows Arch. Pathol Anat., 254, 722–33.Google Scholar
  2. 2.
    Griffin, H.M. (1939) Reverse coarctation with vasomotor gradient: report of cardiovascular anomaly with symptoms of brain tumor. Proc. Mayo Clin., 14, 561–5.Google Scholar
  3. 3.
    Frövig, A.G. (1946) Bilateral obliteration of common carotid artery. Thromboangiitis obliterans? Acta Psychiat. et Neurol. Scandinav., 39 (Suppl.), 4–79.Google Scholar
  4. 4.
    Shimizu, K. and Sano, K. (1951) Pulseless disease. J. Neuropathol. Clin. Neurol., 1, 37–47.Google Scholar
  5. 5.
    Caccamise, W.C. and Whitman, J.F. (1951) Pulseless disease: a preliminary case report. Am. Heart J., 44, 629–33.CrossRefGoogle Scholar
  6. 6.
    Learmonth, B.C. (1952) Report of 16 cases of sudden aortic occlusion. Edinburgh Med. J., 59, 65–93.Google Scholar
  7. 7.
    Ross, R.S. and McKusick, V.A. (1953) Aortic arch syndromes: diminished or absent pulses in arteries arising from arch of aorta. Arch. Inter. Med., 92, 701–40.CrossRefGoogle Scholar
  8. 8.
    Martorell, F. and Fabre, J. (1954) The syndrome of obliteration of the supra-aortic branches. Angiology, 5, 39–42.PubMedCrossRefGoogle Scholar
  9. 9.
    DeBes, L.T., Lucas, J.G.S. and Barcons, F.B. (1955) The case of Takayasu syndrome: the pulseless disease. Br. Heart. J., 17, 484–8.CrossRefGoogle Scholar
  10. 10.
    Barker, N.W. and Edwards, J.E. (1955) Primary arteritis of the aortic arch. Circulation, 11, 486–92.PubMedCrossRefGoogle Scholar
  11. 11.
    Kalmansohn, R.B. and Kalmansohn, R.W. (1957) Thrombotic obliteration of the branches of the aortic arch. Circulation, 15, 237–44.PubMedCrossRefGoogle Scholar
  12. 12.
    Gibbons, T.B. and King, R.L. (1957) Obliterative brachiocephalic arteritis: pulseless disease of Takayasu. Circulation, 15, 845–9.PubMedCrossRefGoogle Scholar
  13. 13.
    Isaacson, C. (1961) An idiopathic aortitis in young Africans. J. Pathol. Bacteriol, 81, 69–79.PubMedCrossRefGoogle Scholar
  14. 14.
    Sen, K.P., Kinare, S.G., Kulkarni, T.P. and Parulkar, G.B. (1962) Stenosing aortitis of unknown etiology. Surgery, 51, 317–25.PubMedGoogle Scholar
  15. 15.
    Inada, K., Shimizu, K. and Yokoyama, T. (1962) Pulseless disease and atypical coarctation of the aorta with special reference to their genesis. Surgery, 52, 433–43.Google Scholar
  16. 16.
    Judge, R.C., Currier, R.D., Graci, W.A. and Figley, M.M. (1962) Takayasu’s arteritis and the aortic arch syndrome. Am. J. Med., 32, 379–92.PubMedCrossRefGoogle Scholar
  17. 17.
    Sen, P.K., Kinare, S.G., Engineer, S.D. and Parulkar, G.B. (1963) The middle aortic syndrome. Br. Heart J., 25, 610–18.PubMedCrossRefGoogle Scholar
  18. 18.
    Strachan, R.W. (1964) The natural history of Takayasu’s arteriopathy. Q. J. Med., 33, 57–69.PubMedGoogle Scholar
  19. 19.
    Nasu, T. and Mamiya, N. (1966) Pathogenesis of truncarteritis productive obliterans; so-called pulseless disease or aortic arch syndrome. Jap. Circ. J., 30, 68–71.CrossRefGoogle Scholar
  20. 20.
    Maekawa, M. and Ishikawa, K. (1966) Occlusive thromboarteriopathy. Jap. Circ., 30, 79–85.CrossRefGoogle Scholar
  21. 21.
    Domingo, R.T., Maramba, T.P., Torres, L.F. and Wesolowski, S.A. (1967) Acquired aortoarteritis. A worldwide vascular entity. Arch. Surg., 95, 780–90.PubMedCrossRefGoogle Scholar
  22. 22.
    Committee Report (1968) Clinical and pathological studies of aortitis syndrome. Jap. Heart J., 9, 76–87.CrossRefGoogle Scholar
  23. 23.
    Marquis, Y., Richardson, J.B., Ritchie, A.C. and Wigle, E.D. (1968) Idiopathic medial aortopathy and arteriopathy. Am. J. Med., 44, 939–54.PubMedCrossRefGoogle Scholar
  24. 24.
    Sen, P.K., Kinare, S.G., Kelkar, M.D. and Paulkar, G.B. (1973) Nonspecific Aorto-arteritis. A Monograph Based on the Study of 101 cases, Tata-McGraw Hill, Bombay.Google Scholar
  25. 25.
    Lie, J.T. (1990) Takayasu arteritis, in Systemic Vasculitides (eds A. Churg, A. Churg and J. Churg), Igaku Shoin, New York, pp. 159–79.Google Scholar
  26. 26.
    Savory, W.S. (1856) Case of a young woman in whom the main arteries of both upper extremities and of the left side of the neck were throughout completely obliterated. Med. Chir. Trans. London, 39, 205–11.Google Scholar
  27. 27.
    Takayasu, M. (1908) A case with unusual changes of the central vessels in the retina. Acta Soc. Ophthalmol. Jap., 35, 750–4.Google Scholar
  28. 28.
    Sharma, S., Kamalakar, T., Rajani, M. et al. (1990) The incidence and patterns of pulmonary artery involvement in Takayasu’s arteritis. Clin. Radiol., 42, 177–81.PubMedCrossRefGoogle Scholar
  29. 29.
    Sharma, S., Rajani, M., Kamalakar, T. et al. (1990) The association between aneurysm formation and systemic hypertension in Takayasu’s arteritis. Clin. Radiol., 42, 182–7.PubMedCrossRefGoogle Scholar
  30. 30.
    Kanaraj, T.J. and Wong, H.O. (1959) Primary arteritis of abdominal aorta in children causing bilateral stenosis of renal arteries and hypertension. Circulation, 20, 856–63.CrossRefGoogle Scholar
  31. 31.
    Wiggelinkhuizen, J. and Cremin, B.J. (1978) Takayasu arteritis and renovascular hypertension in childhood. Pediatrics, 62, 209–17.PubMedGoogle Scholar
  32. 32.
    Kulkarni, T.P., D’Cruz, I.A., Gandhi, M.J. and Dadhich, D.S. (1974) Reversal of renovascular hypertension caused by nonspecific aortitis after corticosteroid therapy. Br. Heart J., 36, 114–16.PubMedCrossRefGoogle Scholar
  33. 33.
    Hall, S., Barr, W., Lie, J.T. et al. (1985) Takayasu arteritis: A study of 32 North American patients. Medicine, 64, 89–99.PubMedCrossRefGoogle Scholar
  34. 34.
    Shelhamer, J.H., Volkman, D.J., Parrillo, J.E. et al. (1985) Takayasu arteritis and its therapy. Ann. Intern. Med., 103, 121–6.PubMedCrossRefGoogle Scholar
  35. 35.
    Hotchi, M. (1993) Pathology of Takayasu arteritis, in Intractable Vasculitis Syndromes (ed. T. Tanabe), Hokaido University Press, Sapporo, pp. 85–92.Google Scholar
  36. 36.
    Nakao, K., Ikeda, M. and Kimatra, S. (1967) Takayasu arteritis: clinical report of eighty-four cases and immunological study of seven cases. Circulation, 35, 1141–55.PubMedCrossRefGoogle Scholar
  37. 37.
    Ishikawa, K. (1986) Patterns of symptoms and prognosis in occlusive throm-boartopathy (Takayasu disease). J. Am. Coll. Cardiol., 8, 1041–6.PubMedCrossRefGoogle Scholar
  38. 38.
    Ishikawa, K. (1988) Diagnostic approach and proposed criteria for the clinical diagnosis of Takayasu’s arteriopathy. J. Am. Coll. Cardiol., 12, 964–72.PubMedCrossRefGoogle Scholar
  39. 39.
    Arend, W.P., Michel, B.A., Bloch, D.A. et al. (1990) The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis. Arthritis Rheum., 33, 1129–34.PubMedCrossRefGoogle Scholar
  40. 40.
    Hall, S. and Buchbinder, R. (1990) Takayasu’s arteritis. Rheum. Dis. Clin. North Am., 16, 411–22.PubMedGoogle Scholar
  41. 41.
    Perniciaro, C.V., Winkelmann, R.K. and Hunder, G.G. (1987) Cutaneous manifestations of Takayasu’s arteritis: a clinicopathologic correlation. J. Am. Acad. Dermatol., 17, 998–1012.PubMedCrossRefGoogle Scholar
  42. 42.
    Hass, A. and Steihm, E.R. (1986) Takayasu’s arteritis presenting as pulmonary hypertension. Am. J. Dis. Child., 140, 372–4.Google Scholar
  43. 43.
    Koumi, S., Endo, T., Okumura, H. et al. (1990) A case of Takayasu’s arteritis associated with membranoproliferative glomerulonephritis and nephrotic syndrome. Nephron. 54, 344–6.PubMedCrossRefGoogle Scholar
  44. 44.
    Koyabu, S., Isaka, N., Yada, T. et al. (1993) Severe respiratory failure caused by recurrent pulmonary hemorrhage in Takayasu’s Arteritis. Chest, 104, 1905–6.PubMedCrossRefGoogle Scholar
  45. 45.
    Cipriano, F., Silverman, J., Perbroth, M. et al. (1977) Coronary ostial narrowing in Takayasu’s arteritis. Am. J. Cardiol., 39, 744–50.PubMedCrossRefGoogle Scholar
  46. 46.
    Tanaka, A., Fukayama, M., Funata, N. et al. (1988) Coronary arteritis and aortoarteritis in the elderly male. Virchows Arch. Pathol Anat., 414, 9–14.CrossRefGoogle Scholar
  47. 47.
    Lande, A. and Bard, R. (1976) Takayasu arteritis: An unrecognized cause of pulmonary hypertension. Angiology, 27, 114–21.PubMedCrossRefGoogle Scholar
  48. 48.
    Chauvaud, S., Mace, L., Brunewald, P. et al. (1987) Takayasu arteritis with bilateral pulmonary artery stenosis: Successful surgical correction. J. Thorac. Cardiovasc. Surg., 94, 246–50.PubMedGoogle Scholar
  49. 49.
    Nasu, T. (1963) Pathology of pulseless disease: A systematic study and critical review of twenty-one autopsy cases reported in Japan. Angiology, 14, 225–42.PubMedCrossRefGoogle Scholar
  50. 50.
    Vinijchaikul, K. (1967) Primary arteritis of the aorta and its main branches (Takayasu arteriopathy): A clinicopathologic autopsy study of cases. Am. J. Med., 43, 15–27.PubMedCrossRefGoogle Scholar
  51. 51.
    Restrepo, C., Tejeda, C. and Correa, P. (1969) Nonsyphilitic aortitis. Arch. Pathol., 87, 1–12.PubMedGoogle Scholar
  52. 52.
    Rose, A.G. and Sinclair-Smith, C.C. (1980) Takayasu arteritis: A study of 16 autopsy cases. Arch. Pathol Lab. Med., 104, 231–7.PubMedGoogle Scholar
  53. 53.
    Lande, A. and Gross, A. (1972) Total aortography in the diagnosis of Takayasu arteritis. Am. J. Radiol., 116, 165–78.Google Scholar
  54. 54.
    Deutch, V., Wexler, L. and Deutch, H. (1974) Takayasu arteritis: An angiographic study with remarks on ethnic distribution in Israel. Am. J. Radiol., 122, 13–28.Google Scholar
  55. 55.
    Lie, Y.Q. and Du, J.H. (1982) Aortoarteritis: A collective angiographic experience in 244 cases. Internat. Angiol., 3, 487–97.Google Scholar
  56. 56.
    Ueda, H., Sugiura, M., Ito, I. et al. (1967) Aortic insufficiency associated with aortitis syndrome. Jap. Heart J., 8, 107–20.PubMedCrossRefGoogle Scholar
  57. 57.
    Lie, J.T. (1987) Segmental Takayasu (giant cell) aortitis with rupture and limited dissection. Hum. Pathol., 18, 1183–5.PubMedCrossRefGoogle Scholar
  58. 58.
    Heggtveit, H., Hanningar, G.R. and Morrione, T.G. (1963) Panaortitis. Am. J. Pathol., 42, 151–72.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 1996

Authors and Affiliations

  • J. T. Lie

There are no affiliations available

Personalised recommendations