Abstract
This chapter deals with conditions caused directly by dietary deficiency of iodine, and because the writer has worked in the west coasts of Scotland and California, both areas where iodine deficiency is rare, the text is based on published data, rather than personal experience. Iodine deficiency is a serious international health problem affecting about 400000000 people in Asia alone. It may cause only goitre, and the term endemic goitre is used when more than 10% of the population have enlargement of the thyroid. In many regions, a considerably higher percentage have this finding. Goitre alone is not a major health hazard, but local complications from goitre are problematic, and become more common as the size of the thyroid increases.
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References
Hetzel, B.S. (1983) Iodine deficiency disorders (IDD) and their eradication. Lancet, 2, 1126–9.
Editorial (1983) From endemic goiter to iodine deficiency disorders. Lancet, 2, 1121–2.
Matovinovic, J. (1983) Endemic goiter and cretinism at the dawn of the third millenium, Ann. Rev. Nutr., 3, 341–412.
Hetzel, B.S. (1986) The concept of iodine deficiency disorders (IDD), in Iodine Deficiency Disorders and Congenital Hypothyroidism, (eds G. Medeiros-Neto, R.M.B. Muriel and A. Halpern), Ache, Sao Paulo, pp. 1–6.
Stanbury, J.B. (1986) Aspects of the clinical findings in endemic goiter, in Iodine Deficiency Disorders and Congenital Hypothyroidism, (eds S.G. Medeiros-Neto, R.M.B. Muriel and A. Halpern), Ache, Sao Paulo, pp. 7–14.
Lu, T.Z. and Ma, T. (1986) A clinical investigation in China on the use of oral versus intramuscular iodized oil in the treatment of endemic goiter, in Iodine Deficiency Disorders and Congenital Hypothyroidism, (eds G. Medeiros-Neto, R.M.B. Muriel and A. Halpern), Ache, Sao Paulo, pp. 103–9.
Pharaoh, P., Delange, F., Fierro-Benitez, R. et al. (1980) Endemie cretinism, in Endemic Goiter and Endemic Cretinism. Iodine Nutrition in Health and Disease, (eds J.B. Stanbury and B.S. Hetzel), John Wiley and Sons Inc, New York, pp. 395–421.
Hetzel, B.S. (1971) The history of endemic cretinism. Instit. Hum. Biol. Papua New Guinea Monograph Series, 2, 5.
McCarrison, R. (1908) Observations on endemic cretinism in the Chitral and Gilgit valleys. Lancet, 2, 1275–80.
Hetzel, B.S. and Hay, I.D. (1979) Thyroid function, iodine nutrition and fetal brain development. Clin. Endocrinol., 11, 445–60.
Pharaoh, P.O.D., Buttfield, I.H. and Hetzel, B.S. (1971) Neurological damage to the fetus resulting from severe iodine deficiency during pregnancy. Lancet, 1, 308–10.
Pharaoh, P.O.D., Buttfield, I.H. and Hetzel, B.S. (1972) The effect of iodine prophylaxis on the incidence of endemic cretinism. Adv. Exp. Med. Biol., 30, 201–21.
Vanderpas, J.B., Rivera-Vanderpas, M.T., Bourdoux, P. et al. (1986) Reversibility of severe hypothyroidism with supplemental iodine in patients with endemic cretinism. N. Engl. J. Med., 315, 791–5.
Pan American Health Organization (1974) Endemic Goiter and Cretinism: Continuing Threats to World Health, (eds J.T. Dunn and G.A. Madeiros-Neto), (PAHO Scientific Publication 292) Pan American Health Organization, Washington DC.
Stanbury, J.B. (1984) The pathogenesis of endemic cretinism. J. Endocrinol. Invest., 7, 409–19.
Medeiros-Neto, G. (1989) Endemic goiter and endemic cretinism, in Endocrinology, (ed. L.J. De Groot), Saunders, Philadelphia, pp. 746–57.
WHO (1979) The Control of Endemic Goiter, (eds E.M. De Maeyer, F.W. Lowenstein and C.H. Thilly), World Health Organization, Geneva.
Stanbury J.B. and Hetzel B.S. (eds) Endemic Goiter and Endemic Cretinism. Iodine nutrition in Health and Disease, John Wiley and Sons Inc, New York.
Medeiros-Neto, G., Muciel R.M.B. and Halpern A. (1986) Iodine Deficiency Disorders and Congenital Hypothyroidism, Ache, Sao Paulo.
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© 1992 I. Ross McDougall
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McDougall, I.R. (1992). Iodine deficiency disorders, endemic goitre and endemic cretinism. In: Thyroid Disease in Clinical Practice. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2881-8_11
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DOI: https://doi.org/10.1007/978-1-4899-2881-8_11
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