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Molecular Mechanisms of Action of Thyroid Hormones

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Book cover Thyroid Hormones

Abstract

The Mechanism of action of any biologically active compound cannot be satisfactorily explained until at least two fundamental questions have been answered: First, what is the process that is changed primarily by the action of this compound and, second, how does the compound modify the process? A subsidiary problem is the discovery of the link between the primary changes in the cell and the whole series of visible, yet outwardly apparently disconnected, effects of the substance at the level of the organ, system, or organism as a whole. The inability to establish such a connection provides a basis for the postulated polyvalent character of the compound, the multiplicity of its points of action, and so on, still so widely held in physiology, pharmacology, and endocrinology.

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Turakulov, Y.K. et al. (1975). Molecular Mechanisms of Action of Thyroid Hormones. In: Turakulov, Y.K. (eds) Thyroid Hormones. Studies in Soviet Science. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2705-7_4

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