Abstract
In the past few years several research groups have measured the diffusion coefficients of components of the respiratory chain in mitochondrial inner membranes (Kawato et al., 1980, 1982; Hochman et al., 1982, 1985; Sowers and Hackenbrock, 1981; Hackenbrock et al., 1986; Vanderkooi et al., 1985; Lenaz and Fato, 1986; Fato et al., 1986). The objective has been to gain insight into the mechanics of electron transfer and the mobility characteristics of this membrane-associated system that may be important in determining the rates and regulation of electron and energy transfer. A major issue is whether this somewhat unusual membrane can best be described as a homogeneous system with randomly diffusing components, or whether it is necessary to invoke a more complex, non-random organization.
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Ferguson-Miller, S., Rajarathnam, K., Hochman, J., Schindler, M. (1988). Is Electron Transfer Mediated by Random Diffusion Alone?. In: Lemasters, J.J., Hackenbrock, C.R., Thurman, R.G., Westerhoff, H.V. (eds) Integration of Mitochondrial Function. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2551-0_3
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