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Disorders of the Hematopoietic System

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Principles and Practice of Environmental Medicine

Abstract

This chapter focuses on the relationship between exposure to environmental chemicals and physical agents and disorders of the hematopoietic system. The hematopoietic system includes the formed elements of the blood as well as the bone marrow, spleen, lymph nodes, and reticuloendothelial tissue. It is uniquely constructed to provide the body with a vast capacity for cell renewal. To balance the loss of mature cells and to provide for rapid expansion in response to bodily insults, cellular renewal must be maintained throughout life. The relative accessibility of the blood and bone marrow creates the potential for providing early clues to the effects of toxic exposure. A wide range of hematological disorders may follow exposure to such environmental agents as solvents, heavy metals, insecticides, nitrates, nitrites, and ionizing radiation (45, 77, 106, 126, 199, 211).

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Recommended Readings

  • Irons RD (ed.): Toxicology of the Blood and Bone Marrow, Raven Press, New York, 1985.

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  • Tsongas TA: Occupational factors in the epidemiology of chemically induced lymphoid and hemopoietic cancers. In: Toxicology of the Blood and Bone Marrow, p 149, Irons RD (ed.), Raven Press, New York, 1985.

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Authors
  1. William A. Newton Jr.
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  2. Alyce Bezman Tarcher
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  1. School of Medicine, University of California, San Francisco, California, USA

    Alyce Bezman Tarcher M.D.

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Newton, W.A., Tarcher, A.B. (1992). Disorders of the Hematopoietic System. In: Tarcher, A.B. (eds) Principles and Practice of Environmental Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2447-6_21

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