Abstract
To exert their various biological activities, glycosaminoglycans such as heparin often bind to specific proteins; over the years, a number of heparin-binding proteins have been identified. In Table 1, we have listed some of the heparin-binding proteins. These are grouped according to the functions they perform. For example, the heparin-binding growth factors presumably have a common function, e.g. all act as mitogens and have very similar sequences. The matrix proteins fibronectin, laminin, vitronectin, and thrombospondin have very different structures, but all can mediate the substrate adhesion of eucaryotic cells.
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© 1992 Springer Science+Business Media New York
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Zhou, F., Höök, T., Thompson, J.A., Höök, M. (1992). Heparin Protein Interactions. In: Lane, D.A., Björk, I., Lindahl, U. (eds) Heparin and Related Polysaccharides. Advances in Experimental Medicine and Biology, vol 313. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2444-5_15
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DOI: https://doi.org/10.1007/978-1-4899-2444-5_15
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