Abstract
Thrombin — a protease with trypsin like specificity — plays a central role in thrombosis and haemostasis. Its conversion of fibrinogen into insoluble fibrin is accompanied by activation of other blood coagulation factors such as V, VIII, XIII, and protein C1.
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Neises, B., Tarnus, C., Broersma, R.J., Bald, C., Rémy, J.M., Heminger, E.F. (1993). The Synthesis and Anticoagulant Activity of Novel Peptidylfluoroalkanes. In: Claeson, G., Scully, M.F., Kakkar, V.V., Deadman, J. (eds) The Design of Synthetic Inhibitors of Thrombin. Advances in Experimental Medicine and Biology, vol 340. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2418-6_16
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DOI: https://doi.org/10.1007/978-1-4899-2418-6_16
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