Abstract
Associated with genotoxic risks is a large body of toxic effects, which include congenital malformations, teratospermia and reduced fertility, spontaneous abortion, miscarriage, and stillbirth, and increased predisposition to various toxic and/or infectious agents. These effects are very difficult to incorporate into genetic hazard assessments because they include traits with irregular, and thus nonpredictable, inheritance patterns as well as self-limiting traits, such as spontaneous abortion, which cannot always be linked directly to genotoxicity.
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© 1987 Springer Science+Business Media New York
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Brusick, D. (1987). Genetic Toxicology and Its Role in the Study of Congenital Malformations. In: Principles of Genetic Toxicology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1980-9_10
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DOI: https://doi.org/10.1007/978-1-4899-1980-9_10
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-1982-3
Online ISBN: 978-1-4899-1980-9
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