Abstract
The human Y chromosome is remarkable not only for the genes it encodes, but, also for the genes it does not encode. Unique among the human chromosomes, the Y chromosome is apparently deficient in genetic information. At a recent official count1, over 100 genes were assigned to the human X chromosome. As the Y chromosome is approximately one third the size of the X, it might be expected that 30 genes would have been mapped to the Y. Even if all the “may be” and “perhaps” assignments are included, only 7 genes have been mapped to the Y chromosome and, of these, only a single gene has passed the final test of being cloned and subjected to sequence analysis2, 3.
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Goodfellow, P.N., Goodfellow, P.J., Pym, B., Banting, G., Pritchard, C., Darling, S.M. (1987). Genes on the Human Y Chromosome. In: Haseltine, F.P., McClure, M.E., Goldberg, E.H. (eds) Genetic Markers of Sex Differentiation. Reproductive Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1965-6_9
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DOI: https://doi.org/10.1007/978-1-4899-1965-6_9
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