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Calcium and Exocytosis

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Integrative Aspects of Calcium Signalling

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Abstract

Substances destined for export from eukaryotic cells are packed into membrane vesicles (or granules). Exocytosis is the process of fusion of these vesicles with the plasma membrane whereby soluble components from the vesicle interior are released outside and the membrane of the vesicle is integrated into the plasma membrane. Thus, exocytosis acts not only as an outwardly directed activity of the cell, but also fulfils an important role in the intracellular exchange of membranes. Exocytosis increases the area of the plasma membrane. The opposite process, endocytosis involves a membrane invagination and fission of a vesicle into the cell with a consequent decrease in the plasma membrane area.

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  1. Max-Delbrück Center for Molecular Medicine, Robert-Rössle Straße 10, D-13122, Berlin-Buch, Germany

    Jana Hartmann

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    Alexej Verkhratsky

  2. Department of Physiology, Birmingham University Medical School, Birmingham, B15 2TT, UK

    Emil C. Toescu

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Hartmann, J. (1998). Calcium and Exocytosis. In: Verkhratsky, A., Toescu, E.C. (eds) Integrative Aspects of Calcium Signalling. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1901-4_11

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  • DOI: https://doi.org/10.1007/978-1-4899-1901-4_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1903-8

  • Online ISBN: 978-1-4899-1901-4

  • eBook Packages: Springer Book Archive

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