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Mixed Natural Antioxidants

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Book cover Food and Free Radicals
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Abstract

Cancer, inflammation, diabetes, cardiovascular disease, neurological diseases and many other diseases have been shown to be related to free radicals. In the case of neurological diseases such as dementia, stroke, and tumor, much effect has been concentrated on the study of free radicals1. Recently, food with antioxidant properties has been suggested as a prophylactic for the above diseases. A specially designed mix of natural antioxidants has been recommended as a prophylactic. In the chapter, the free radical scavenging activity of mixed natural antioxidants is described using electron spin resonance (ESR) spectrometry.

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References

  1. L. Packer, L. Prilipko and Y. Christen (eds), Free Radicals in the Brain — Aging, Neurological and Mental Disorders (1992), Springer-Verlag, Berlin/Heidelberg, Germany.

    Google Scholar 

  2. Hiramatsu, M., Edamatsu, R., Kohno, M. and Mori, A. (1988) Scavenging of free radicals by Sho-saiko-to-go-keishi-ka-shakuyaku-to (TJ-960). In: E. Hosoya and Y. Yamamura (eds), Recent Advances in the Pharmacology of KAMPO MEDICINES, pp. 120–127. Excerpta Medica, Tokyo.

    Google Scholar 

  3. Hiramatsu, M., Velasco, R.D. and Packer, L. (1990) Vitamin E radical reaction with antioxidants in rat liver membranes. Free Rad. Biol. Med. 9, 459–464.

    Article  CAS  Google Scholar 

  4. Hiramatsu, M., Edamatsu, R., Kabuto, H. and Mori, A. (1988) Effect of Sho-saiko-to-go-keishi-ka-shakuyaku-to (TJ-960) on monoamines, amino acids, lipid peroxides, and Superoxide dismutase in brains of aged rats. In: E. Hosoya and Y. Yamamura (eds), Recent Advances in the Pharmacology of KAMPO MEDICINES, pp. 128–135. Excerpta Medica, Tokyo.

    Google Scholar 

  5. Hiramatsu, M., Kabuto, H. and Mori, A. (1986) Effect of Shosaikoto-go-keishikashakuyakuto (TJ-960) on brain catecholamine level of aged rats. IRCS Med. Sci. 14, 189–190.

    Google Scholar 

  6. Hiramatsu, M., Haba, K., Edamatsu, R., Hamada, H. and Mori, A. (1989) Increased choline acetyltransferase activity by Chinese herbal medicine Shosaiko-to-go-keishi-ka-shakuyaku-to in aged rat brain. Neurochem. Res. 14, 249–251.

    Article  CAS  Google Scholar 

  7. Nagakubo, S., Niwa, S., Kumagai, N., Fukuda, M., Anzai, N., Yamauchi, T., Aikawa, H., Toyoshima, R., Kojima, T., Matsuura, M., Ookubo, Y. and Ootaka, T. (1993) Effects of TJ-960 on sternberg’s paradigm results in epileptic patients. Jpn. J. Psychiat. Neurol. 47, 609–620.

    CAS  Google Scholar 

  8. Sugimoto, T., Ishige, A., Sudo, K., Sekiguchi, K., Iizuka, S., Itoh, K., Yuzurihara, M., Aburada, M., Hosoya, E. and Sugaya, E. (1988) Protective effect of Sho-saiko-to-go-keishika-shakuyaku-to (TJ-960) against cerebral ischemia. In: E. Hosoya and Y. Yamamura (eds), Recent Advances in the Pharmacology of KAMPO MEDICINES, pp. 112–112. Excerpta Medica, Tokyo.

    Google Scholar 

  9. Hiramatsu, M., Komatsu, M. and Ueda, Y. Aging and herbal antioxidants. In: W. Xin, L. Packer and F. Gu (eds), Natural Antioxidants: Molecular Mechanisms and Health Effects, AOCS Press, in press.

    Google Scholar 

  10. Hamada, H., Hiramatsu, M. and Mori, A. (1993) Free radical scavenging action of bicalein. Arch. Bio-chem. Biophys. 306, 261–266.

    Article  CAS  Google Scholar 

  11. Hagino, N. and Koyama, T. (1988) Stimulation of nicotine acetylcholine receptor synthesis in the brain by Toki-shakuyaku-san (TJ-23). In: E. Hosoya and Y. Yamamura (eds), Recent Advances in the Pharmacology of KAMPO MEDICINES, pp. 144–149. Excerpta Medica, Tokyo.

    Google Scholar 

  12. Toriizuka, K. (1995) Effect of Toki-shakuyaku-san on central nervous system, memory and immune reaction. Modern Physician 15, 376–383.

    Google Scholar 

  13. Ueda, Y., Komatsu, M. and Hiramatsu, M. Free radical scavenging activity of Japanese herbal medicine, Toki-shakuyaku-san (TJ-23), and TJ-23 increased Superoxide dismutase activity and decreased concentration of lipid peroxide, glutamate and monoamine metabolites in aged rat brain. Neurochem. Res. in press.

    Google Scholar 

  14. Kudo, T. and Sugiura, K. (1992) Toki-shakuyaku-san and aged dementia. Iyaku Journal 28, 35–38 (in Japanese).

    Google Scholar 

  15. Totsuka, S. and Kawakatsu, S. (1991) The treatment of Toki-shakuyaku-san on aged dementia. Gendai-Toyo-Igaku 12, 315–317 (in Japanese).

    Google Scholar 

  16. Liu, J., Hiramatsu, M. and Mori, A. (1991) Free radical scavenging activity in Ganoderma Lucidum (Fr.) Karst. The Clinical Report 25, 317–321 (Abstract in English).

    Google Scholar 

  17. Hohjoh, T., Hiramatsu, M., Komatsu, M. and Takagi, N. (1995) Free radical scavenging action of GEO REISHI 103. Magnetic Resonance in Medicine 6, 312–314.

    Google Scholar 

  18. Liu, J., Wang, Z.X., Hiramatsu, M. and Mori, A. (1992) Free radical scavenging activity of Kanglaojian-shenye— A possible mechanism of its anti aging effect. Magnetic Resonance in Medicine 3, 134–137 (Abstract in English).

    Google Scholar 

  19. Komatsu, M. and Hiramatsu, M. (1995) Free radical scavenging activity of Long-life SOD. Clinical report 29, 69–74 (Abstract in English).

    Google Scholar 

  20. Liu, J. and Mori, A. (1993) Free radical scavenging and antiperoxidative effect of Frucutus Momordicae. The Clinical Report 27, 257–263.

    Google Scholar 

  21. Packer, L. (1995) Nutrition and biochemistry of the lipophilic antioxidants vitamin E and carotenoids. In: A.S.H. Ong, E. Niki and L. Packer (eds), Nutrition, Lipids, Health, and Disease, pp. 8–35. AOCS Press, USA.

    Google Scholar 

  22. Uchida, S., Edamatsu, R., Hiramatsu, M., Mori, A., Nonaka, G., Nishioka, I., Niwa, M. and Ozaki, M. (1987) Condensed tannins scavenger active oxygen free radicals. Med. Sci. Res. 15, 831–832.

    CAS  Google Scholar 

  23. Matsuzaki, T. and Hara, Y. (1985) Antioxidative activity of tea leaf catechins. J. Agr. Chem. Soc. Jap., 59, 129–134.

    CAS  Google Scholar 

  24. Hara, Y., Matsuzaki, S. and Nakamura, K. (1989) Anti-tumor activity of tea catechins. J. Jpn. Soc. Nutr. Food Sci., 42, 39–45.

    Article  CAS  Google Scholar 

  25. Hara, Y. and Tonooka, F. (1990) Hypotensive effect of tea catechins on blood pressure of rats. J. Jpn. Soc. Nutr. Food Sci., 43, 345–348.

    Article  CAS  Google Scholar 

  26. Maeda, Y., Yamamoto, M., Matui, T., Sugiyama, K., Yokota, M., Nakagomi, K., Tanaka, H., Takahashi, T. and Kobayashi, T. (1989) Inhibitory effect of tea extract on histamine release from mast cells. J. Food Hyg. Soc. 30, 295–299.

    Article  CAS  Google Scholar 

  27. Yoneda, T., Hiramatsu, M., Sakamoto, M., Togasaki, K., Komatsu, M. and Yamaguchi, K. (1995) Antioxidant effects of “β-CATECHIN”. Biochem. Mol. Biol. Int. 35, 995–1008.

    CAS  Google Scholar 

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© 1997 Springer Science+Business Media New York

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Hiramatsu, M. (1997). Mixed Natural Antioxidants. In: Hiramatsu, M., Yoshikawa, T., Inoue, M. (eds) Food and Free Radicals. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1837-6_10

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  • DOI: https://doi.org/10.1007/978-1-4899-1837-6_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1839-0

  • Online ISBN: 978-1-4899-1837-6

  • eBook Packages: Springer Book Archive

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