Cell Membrane Permeability- and Mitochondrial Dysfunction-Inducing Activities in Cell Free Supernatants from Serpulina Hyodysenteriae Serotypes 1 and 2

  • N. A. Witters
  • G. E. Duhamel
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 412)


Serpulina hyodysenteriae is a Gram-negative, anaerobic, oxygen-tolerant spirochete recognized as the etiologic agent of swine dysentery. Currently 9 serotypes/serogroups of S. hyodysenteriae are recognized on the basis of antigenicity of cell wall lipooligosaccharide antigens. Characteristics that distinguish S. hyodysenteriae from other intestinal spirochetes of swine include strong hemolytic activity and enteropathogenicity for swine, mice, guinea pigs and chicks.


Toxic Activity Cell Free Supernatant Cell Membrane Permeability American Veterinary Medical Association Peripheral Blood Lympho 
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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • N. A. Witters
    • 1
  • G. E. Duhamel
    • 1
  1. 1.Department of Veterinary and Biomedical SciencesUniversity of NebraskaLincolnUSA

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