Abstract
Six cases of necrotising fasciitis (NF) five confirmed and one probable, caused by group A streptococci (GAS) in residents of Gloucestershire were reported within a three month period in 1994. Two patients died. Two cases were post operative infections which occurred following routine operations within one week. The other cases were thought to be community acquired1. As a result of this cluster of severe infections within one geographic locality a PHLS Action Group was established to discuss strategies and the implications of this incident. The group agreed a case definition for surveillance purposes and recommended that an enhanced programme of surveillance of severe group A streptococcal infections should be set up in England and Wales. This has now been successfully established. Information relating to trends in severe GAS disease at that time did not suggest that there had been a sudden increase in disease. Twenty six cases of GAS necrotising fasciitis were reported in England and Wales with dates of onset during the first six months of 1994. The case fatality rate was 69% However, routine surveillance was unable to provide a precise figure of the number of cases of NF associated with GAS infections in England and Wales prior to the Enhanced Surveillance Scheme. Data from this survey, combined with data from other countries gave estimates of 45 to 120 cases of GAS NF each year. Preliminary analysis of 847 cases of invasive GAS disease during the surveillance period of July 1994 to February 1996 has shown that they included 56 confirmed cases of NF of which 53% of patients had died.
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© 1997 Springer Science+Business Media New York
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Efstratiou, A. et al. (1997). Characterisation of Group A Streptococci from Necrotising Fasciitis Cases in Gloucestershire, United Kingdom. In: Horaud, T., Bouvet, A., Leclercq, R., de Montclos, H., Sicard, M. (eds) Streptococci and the Host. Advances in Experimental Medicine and Biology, vol 418. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1825-3_23
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DOI: https://doi.org/10.1007/978-1-4899-1825-3_23
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