Surface Protein Expression in Group B Streptococcal Invasive Isolates

  • Patricia Ferrieri
  • Aurea E. Flores
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 418)

Abstract

Group B streptococci (GBS) are important pathogens of newborn infants, causing sepsis and/or meningitis, of early-onset or late-onset. GBS also cause bacteremia in parturients, the elderly and the immunocompromised.1 Identification of GBS isolates is based on the type polysaccharide (serotypes Ia through VIII) and the surface-localized c and R proteins.1, 5 C protein includes two components: trypsin sensitive beta (β) and trypsin resistant alpha (α)5 while R includes four species, R1 through R4 and, like α, is trypsin-resistant.3 These proteins are of interest because of their possible role in GBS virulence and protective immunity.

Keywords

Agarose Polysaccharide Trypsin Polyacrylamide Resis 

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References

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    Ferrieri, P. Surface-localized protein antigens of group B streptococci. Rev. Infect. Dis. 10(Suppl. 2):S363–S366, 1988.PubMedCrossRefGoogle Scholar
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    Flores, A.E. and P. Ferrieri. Molecular diversity among the trypsin resistant surface proteins of group B streptococci. Zbl. Bakt. (International Journal of Medical Microbiology, Virology, Parasitology & Infectious Diseases) 285: 44–51, 1996.Google Scholar
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    Flores, A.E. and P. Ferrieri. Molecular species of R-protein antigens produced by clinical isolates of group B streptococci. J. Clin. Microbiol. 27:1050–1054, 1989.PubMedGoogle Scholar
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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Patricia Ferrieri
    • 1
  • Aurea E. Flores
    • 1
  1. 1.Departments of Laboratory Medicine and Pathology and PediatricsUniversity of Minnesota Medical SchoolMinneapolisUSA

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