Eicosanoids and other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 3 pp 491-495 | Cite as
Formation of Eicosanoids during Differentiation of Thp-1 Cells
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Abstract
Monocytes and macrophages play important roles in many host reactions. They can mediate immune and inflammation processes via the production and release of a variety of soluble mediators such as radicals like Superoxide anions (O2 −), cytokines like tumor necrosis factor a (TNF-α) and eicosanoids like prostaglandin E2 (PGE2). These biological active agents are also known to modulate cell differentiation and proliferation.
Keywords
Latex Bead Monocytic Leukemia Calcium Ionophore A23187 Cytosolic Phospholipase Human Monocytic Leukemia Cell
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© Springer Science+Business Media New York 1997