Abstract
Atopy is primarily a condition of hypersensitivity. Atopic disease include atopic eczema, allergic bronchial asthma or hay fever. Atopic dermatitis signs and symptoms are dry itching skin, and eczematous inflammation. Pathophysiology involve: genetics, trigger factors as aeroallergens, superantigens or stress, Th2 lymphocyte cytokine profile (Interleukin (IL)-4,-5,-10) dominance, hyper IgE, monocyte phosphodiesterase increased activity, impaired epidermal barrier function and abnormal linoleic acid metabolism.
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Giménez-Arnau, A. et al. (1997). Effects of Linoleic Acid Supplements on Atopic Dermatitis. In: Sinzinger, H., Samuelsson, B., Vane, J.R., Paoletti, R., Ramwell, P., Wong, P.YK. (eds) Recent Advances in Prostaglandin, Thromboxane, and Leukotriene Research. Advances in Experimental Medicine and Biology, vol 433. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1810-9_60
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DOI: https://doi.org/10.1007/978-1-4899-1810-9_60
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