Abstract
Volume regulation is a property common to many animal cell types (for references, see reviews1, 2) and when exposed to anisotonic media they modify their intracellular concentration of osmolytes by activation of permeability pathways, leading to osmotically-driven water shifts. In response to swelling induced by hypotonicity, cells lose KC1 and organic osmolytes to recover their normal volume, a process known as regulatory volume decrease (RVD).
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Stutzin, A., Eguiguren, A.L., Cid, L.P., Sepúlveda, F.V. (1997). Anion Channels Involved in Volume Regulation: A Common Pathway for Chloride and Organic Osmolyte Permeation?. In: Latorre, R., Sáez, J.C. (eds) From Ion Channels to Cell-to-Cell Conversations. Series of the Centro de Estudios Científicos de Santiago. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1795-9_14
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DOI: https://doi.org/10.1007/978-1-4899-1795-9_14
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