Antioxidant Activity of Vitamin A within Lipid Environments

  • Maria A. Livrea
  • Luisa Tesoriere
Part of the Subcellular Biochemistry book series (SCBI, volume 30)


New information about deleterious effects of free radicals on cell compartments, and a growing amount of associations between free radicals and various pathological conditions, have produced considerable interest in the biological defense systems against oxidative injury. The antioxidant properties of vitamin A, known for decades (Monaghan and Schmitt, 1932), have been reinvestigated in recent years in chemical as well as in biological systems. Its lipid nature and the localization within the lipophilic compartment of membranes and lipoproteins make vitamin A effective in reducing lipid peroxidation by acting as a chain-breaking antioxidant.


Lipid Peroxidation Antioxidant Activity Retinoic Acid Peroxyl Radical Retinyl Palmitate 
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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Maria A. Livrea
    • 1
  • Luisa Tesoriere
    • 1
  1. 1.Istituto di Farmacologia e FarmacognosiaUniversità di PalermoPalermoItaly

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