Plant Acyl-ACP Thioesterases: Chain-Length Determining Enzymes in Plant Fatty Acid Biosynthesis

  • Toni Voelker
Part of the Genetic Engineering book series (GEPM, volume 18)


De novo plant fatty acid biosynthesis takes place in an organelle, the plastid. Acyl chains are elongated by 6 to 7 dissociable enzymes, together constituting a so-called type II fatty acid synthase. During the extension cycles the acyl chains are covalently bound, via a thioester, to the prosthetic group of a small, soluble, acyl carrier protein (ACP; 78 amino acid residues) (1,2). Taken together, these features make the plant fatty acid synthase distinct from the cytoplasmic, multi-subunit fatty acid synthase of animals and fungi (type I), but quite similar to the one common in prokaryotes (3). This functional similarity is one of the many vestiges of the prokaryotic ancestry of the plastids, which descended from cyanobacterial endosymbionts (4).


Fatty Acid Biosynthesis Transit Peptide Medium Chain Petroselinic Acid International Patent Application 
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© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Toni Voelker
    • 1
  1. 1.Calgene, Inc.DavisUSA

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