The Lysozyme Cistron of T4 Phage
The genetic message is translated sequentially, three bases at time, starting from a defined AUG codon at the begining a cistron (Crick et al., 1961; Terzaghi et al., 1966). Deletions or additions of bases cause a shift in the reading frame of the genetic message and, therefore, such changes are called frame-shift mutations.
KeywordsMutant Strain Genetic Code Lysozyme Activity Dilute Acid Hydrolysis Lysozyme Gene
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- Owen, E. J., 1971 Some genetic studies of bacteriophage T4. Ph.D. Thesis, University of Oregon, Eugene, Oregon.Google Scholar
- Tsugita, A., M. Inouye, T. Imagawa, T. Nakanishi, Y. Okada, J. Emrich and G. Streisinger, 1969 Frame-shift mutations resulting in the changes of the same amino acid residue (140) in T4 bacteriophage lysozyme and in vivo codons for Trp, Tyr, Met, Val and Ile. J. Mol. Biol. 41:349–364.PubMedCrossRefGoogle Scholar