Expression of the ABH, Lewis, and Related Antigens on the Glycoproteins of the Human Jejunal Brush Border

  • F. R. Green
  • P. Greenwell
  • L. Dickson
  • B. Griffiths
  • J. Noades
  • D. M. Swallow
  • P. Greenwell
Part of the Subcellular Biochemistry book series (SCBI, volume 12)


The ABH and Lewis antigens are carbohydrate structures that occur on the surface of certain hemopoietic and epithelial cells and in many body fluids. The role of the ABO, Se, H, and Le gene loci and their glycosyltransferase products in determining the structures and the genetic polymorphisms of these terminal carbohydrate antigens has been reviewed in detail elsewhere (Oriol et al., 1986; Watkins, 1980). The biochemical pathways are shown in summary form in Figure 1.


Blood Group Secretor Status Pyloric Gland Human Erythrocyte Membrane Lewis Antigen 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • F. R. Green
    • 1
  • P. Greenwell
    • 1
  • L. Dickson
    • 1
  • B. Griffiths
    • 1
  • J. Noades
    • 1
  • D. M. Swallow
    • 1
  • P. Greenwell
    • 2
  1. 1.MRC Human Biochemical Genetics UnitUniversity CollegeLondonUK
  2. 2.Division of Immunochemical GeneticsMRC Clinical Research CentreHarrowUK

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