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Molecular Karyotype Analysis in Leishmania

  • Patrick Bastien
  • Christine Blaineau
  • Michel Pagès
Part of the Subcellular Biochemistry book series (SCBI, volume 18)

Abstract

Leishmania is a flagellated protozoan parasite belonging to the order Kinetoplastida and to the family Trypanosomatidae. A total number of 25 species has been described,* grouped in at least 12 complexes (Lainson and Shaw, 1972, 1987; Rioux, 1986; Rioux et al., 1990). They are responsible for a wide spectrum of human diseases, mostly in the tropics and subtropics, ranging from sometimes relatively benign cutaneous disease (L. major, L. tropica, L. mexicana, L. panamensis) to mutilating mucocutaneous and diffuse cutaneous lesions (L. braziliensis, L. amazonensis, L. aethiopica), and potentially fatal visceral disease affecting the hematopoietic organs (L. donovani, L. infantum, L. chagasi). Leishmaniasis has been estimated to affect 20 million people, mainly in poor countries from both the Old and the New World (Barker, 1987).

Keywords

Homologous Chromosome Pulse Time Karyotype Analysis Chromosomal Band Small Chromosome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Patrick Bastien
    • 1
  • Christine Blaineau
    • 1
  • Michel Pagès
    • 2
  1. 1.Laboratoire d’Ecologie Médicale et Pathologie ParasitaireAnnexe de la Faculté de MédecineMontpellierFrance
  2. 2.Centre de Recherche de Biochimie Macromoleculaire du CNRS et Unité 249 de l’INSERMMontpellier CedexFrance

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