Abstract
An emerging body of evidence has established that mammalian embryogenesis is under the control of polypeptide molecules that influence not only growth, but differentiation and morphogenesis during mammalian development. Growth factors exert their regulatory functions by acting in an autocrine or paracrine mode. These embryonic polypeptide growth factors are usually identical to growth factors isolated from serum or tissues of adult animals. Insulin-like growth factor II (IGF-II) (for a review see Schofield, 1992) is one of the growth factors playing a significant role in the development of the mammalian embryo.
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Stylianopoulou, F. (1995). The Role of Insulin-Like Growth Factor II in the Growth and Development of the Mammalian Embryo. In: Zagris, N., Duprat, A.M., Durston, A. (eds) Organization of the Early Vertebrate Embryo. NATO ASI Series, vol 279. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1618-1_9
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DOI: https://doi.org/10.1007/978-1-4899-1618-1_9
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