Abstract
Urinary excretion is an essential aspect of body homeostasis and therefore appears at an early stage of fetal development. In the primitive lower urinary tract, storage and elimination of urine are presumably mediated by nonneural mechanisms; however at later stages of fetal and postnatal life these mechanisms are regulated by neural pathways that trigger involuntary or reflex voiding. As the nervous system matures during the postnatal period reflex voiding is eventually subject to voluntary control which originates in higher centers in the brain (1). Thus, the functions of the lower urinary tract can be grouped according increasing levels of complexity from the most primitive which are intrinsic to the target organs to the most complicated which require the participation of the cerebral cortex.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
de Groat, W. C., A. M. Booth, and N. Yoshimura. Neurophysiology of micturition and its modification in animal models of human disease. In: The Autonomic Nervous System, Vol. 3, Nervous Control of the Urogenital System, edited by C. A. Maggi. London: Harwood Academic Publishers, p. 227–290, 1993.
Spitzer, N. C. A developmental handshake: Neuronal control of ionic currents and their control of neuronal differentiation. J. Neurobiol 22: 659–673, 1991.
Dourado, M. M. and S. E. Dryer. Regulation of A-currents by cell-cell interactions and neurotrophic factors in developing chick parasympathetic neurones. J. Physiol. 474: 367–377, 1994.
Rao, M. S. and S. C. Landis. Cell interactions that determine sympathetic neuron transmitter phenotype and the neurokines that mediate them. J. Neurobiol. 24(2): 215–232, 1993.
Sugaya, K. and W. C. de Groat. Micturition reflexes in the in vitro neonatal rat brainstemspinal cord-urinary bladder preparation. Am. J. Physiol. 266: R658–R667, 1994.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer Science+Business Media New York
About this chapter
Cite this chapter
de Groat, W.C. (1995). Developmental Physiology-Overview. In: Zderic, S.A. (eds) Muscle, Matrix, and Bladder Function. Advances in Experimental Medicine and Biology, vol 385. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1585-6_10
Download citation
DOI: https://doi.org/10.1007/978-1-4899-1585-6_10
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-1587-0
Online ISBN: 978-1-4899-1585-6
eBook Packages: Springer Book Archive