Abstract
The K mutation determines a variant butyrylcolinesterase (BChE) whose retarded synthesis or accelerated degradation leads to a 33% reduction of activity in comparison to the usual enzyme (1). The BCHE UK and BCHE K phenotypes are only identified by direct DNA analysis, since the quantitative effect of the K mutation cannot be detected by enzyme inhibition tests.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Rubinstein et al. J. Med. Genet., 15:21–29, 1978.
Shibuta et al. J. Med. Genet., 31:576–579, 1994.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1998 Springer Science+Business Media New York
About this chapter
Cite this chapter
Souza, R.L.R., Castro, R.M.V., Pereira, L., Freund, A.A., Culpi, L., Chautard-Freire-Maia, E.A. (1998). Frequencies of the Butyrylcholinesterase K Mutation in Southern Brazilian Population Samples of European and African Origin. In: Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. (eds) Structure and Function of Cholinesterases and Related Proteins. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1540-5_163
Download citation
DOI: https://doi.org/10.1007/978-1-4899-1540-5_163
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-1542-9
Online ISBN: 978-1-4899-1540-5
eBook Packages: Springer Book Archive