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Cardioprotective Actions of Taurine against Intracellular and Extracellular Calcium-Induced Effects

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Taurine in Health and Disease

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 359))

Abstract

Taurine, a sulfur-containing amino acid, is present in myocardial cells at high concentration (around 10 mM) (13). Taurine produces many functions on the ion fluxes across cell membrane and the contractile force (13,31,33,34). It has already been reported that taurine produces a positive inotropic effect in heart muscles (3,7,8,10), that it has beneficial effects in treatment of congestive heart failure (2,36), and that is is protective against Ca2+ overload and cardiomyopathy (1,19,37). Taurine levels in the cells are lowered in ischemic heart failure (17,18).

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Authors and Affiliations

  1. Department of Pharmacology, Nara Medical University, Kashihara, Nara 634, Japan

    Hiroyasu Satoh

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  1. Hiroyasu Satoh
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Editors and Affiliations

  1. College of Medicine, University of Arizona, Tucson, Arizona, USA

    Ryan J. Huxtable

  2. University of Cologne, Cologne, Germany

    Dietrich Michalk

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© 1994 Springer Science+Business Media New York

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Satoh, H. (1994). Cardioprotective Actions of Taurine against Intracellular and Extracellular Calcium-Induced Effects. In: Huxtable, R.J., Michalk, D. (eds) Taurine in Health and Disease. Advances in Experimental Medicine and Biology, vol 359. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1471-2_19

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  • DOI: https://doi.org/10.1007/978-1-4899-1471-2_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1473-6

  • Online ISBN: 978-1-4899-1471-2

  • eBook Packages: Springer Book Archive

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