Neurochemical and Behavioral Sequelae of Exposure to Dioxins and PCBs

  • Richard F. Seegal
  • Susan L. Schantz


In a previous review of the literature related to the toxicity of polychlorinated biphenyls (PCBs), one of the present authors1 reviewed the experimental evidence demonstrating that one of the major classes of PCBs—the ortho-substituted congeners—were capable of altering neurological function in a wide variety of experimental preparations. In this chapter we broaden the review to include a discussion of the behavioral effects of exposure as well as contributions that coplanar PCBs, dioxins (PCDDs), and di-benzofurans (PCDFs) make to the overall neurotoxic risk to humans from exposure to complex environmental mixtures.


Wisconsin Card Sort Test Central Nervous System Function Perinatal Exposure Wisconsin General Test Apparatus Behavioral Sequela 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Richard F. Seegal
    • 1
  • Susan L. Schantz
    • 2
  1. 1.New York State Department of HealthWadsworth Center for Laboratories and ResearchAlbanyUSA
  2. 2.School of Public HealthUniversity at Albany, State University of New YorkAlbanyUSA

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