Abstract
Lethal effects of particles have been investigated over a wide range of LET values (for a review, see Kraft (1987)). For high-LET ions (> 100 keV/μm) survival curves display exponential dependence versus fluence: inactivation cross sections are given as l/F1/e, where F1/e is the fluence for 1/e percentage of surviving cells. For highly energetic ions with lower LET-values, a shoulder appears at small fluence, indicating repair process: the cross section is then calculated from the final slope of the curve.
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Chetioui, A., Guiraud, L., Despiney, I., Sabatier, L. (1995). Physical Mechanisms for Cellular Inactivation Induced by ION Impact. In: Liesen, D. (eds) Physics with Multiply Charged Ions. NATO ASI Series, vol 348. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1412-5_15
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DOI: https://doi.org/10.1007/978-1-4899-1412-5_15
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