Abstract
Pertussis and cholera endure as major contributors to worldwide morbidity and mortality. Even with efficacious vaccines against pertussis long available, it was not until recently that a significant reduction in the global incidence of infant disease has been recorded as a result of the successes of national and global vaccine initiatives. In contrast, no meaningfully effective vaccine exists for cholera, with the result that more than eight million cases of this disease and 150,000 cholera-related deaths occur each year.
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Burnette, W.N. (1996). Parameters for the Rational Design of Genetic Toxoid Vaccines. In: Cohen, S., Shafferman, A. (eds) Novel Strategies in the Design and Production of Vaccines. Advances in Experimental Medicine and Biology, vol 397. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1382-1_9
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DOI: https://doi.org/10.1007/978-1-4899-1382-1_9
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