Receptors for (3–8) Angiotensin in Brain Cells

AngIV Binding in Brain Cells
  • Conrad Sernia
  • Bruce Wyse
  • Siok-Keen Tey
  • Su-Lin Leong
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 396)


Angiotensin II (AngII) is the peptide effector hormone of the blood renin-angiotensin system (RAS). Central to the role of the RAS as a hormonal regulator of cardiovascular function are the actions of AngII on vascular tone and on fluid and electrolyte homeostasis (1). It is commonly accepted that the functions of the blood RAS are supported by local angiotensin-generating systems in various tissues, including the heart, kidney, adrenal, blood vessels and brain (2–4). Hence, production of Angll in particular brain areas can lead to hypertensive changes in the periphery.(3,5,6).


High Pressure Liquid Chromatography Radioreceptor Assay Phase High Pressure Liquid Chromatography Primary Glial Cell AngII Receptor 
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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Conrad Sernia
    • 1
  • Bruce Wyse
    • 1
  • Siok-Keen Tey
    • 1
  • Su-Lin Leong
    • 1
  1. 1.Neuroendocrine Laboratory, Department of Physiology and PharmacologyUniversity of QueenslandQueenslandAustralia

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