Brain Angiotensin II and Related Receptors: New Developments

  • J. M. Saavedra
  • A. M. de Oliveira
  • O. Jöhren
  • M. Viswanathan
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 396)


Our research has recently been focused on the characterization and role of brain angiotensin II receptor subtypes (1). In a manner similar to that of the periphery (2), brain angiotensin II receptors were initially characterized in two subtypes, AT1 and AT2 (1,3).


Receptor Subtype Inferior Olive Related Receptor Gerbil Brain Gerbil Hippocampus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Saavedra, J.M. (1992) Endocr. Rev. 13: 329–380.PubMedGoogle Scholar
  2. 2.
    Timmermans, P.B.M.W.M., Wong, P.C., Chiu, A.T., Herblin, W.F., Benfield, P., Carini, D.J., Lee, R.J., Wexler, R.R., Saye, J.A.M. and Smith, R.D., 1993, Pharmacol. Rev. 45: 205–251.PubMedGoogle Scholar
  3. 3.
    Tsutsumi, K. and Saavedra, J.M. (1991). Am. J. Physiol. 261: R209–R216.PubMedGoogle Scholar
  4. 4.
    Tsutsumi, K. and Saavedra, J.M. (1991). Endocrinology 129: 3001–3008.PubMedCrossRefGoogle Scholar
  5. 5.
    Tsutsumi, K. and Saavedra, J.M. (1991). Am. J. Physiol. 261: H663–H670.Google Scholar
  6. 6.
    Strömberg, C., Naveri, L. and Saavedra, J.M. (1993) J. Cereb. Blood Flow Metab. 13: 298–303.PubMedCrossRefGoogle Scholar
  7. 7.
    Iwai, N. and Inagami, T. (1992). FEBS 298: 257–260.CrossRefGoogle Scholar
  8. 8.
    Yoshida, H., Kukuchi, J., Guo, D.F., Furuta, H., Iwai, N., van del Meer-de Jong, R., Inagami, T. and Ichikawa, I. (1992). Biochem. Biophys. Res. Commun. 186: 1042–1049.PubMedCrossRefGoogle Scholar
  9. 9.
    Tsutsumi, K. and Saavedra, J.M. (1992). Mol. Pharmacol. 41: 290–297.PubMedGoogle Scholar
  10. 10.
    Allen, K.L., Busza, A.L., Proctor, E., King, M.D., Williams, S.R., Crockard, H.A. and Gadian, D.G. (1993). NMR in Biomedicine, 6: 181–186.PubMedCrossRefGoogle Scholar
  11. 11.
    Crain, B.J., Westerkam, W.D., Harrison, A.H. and Nadler, J.V. (1988). Neuroscience 27: 387–402.PubMedCrossRefGoogle Scholar
  12. 12.
    Berry, K., Wisniewski, H.M., Svarzbein L. and Baez, S. (1975). J. Neurol. Sci. 25: 75–92.PubMedCrossRefGoogle Scholar
  13. 13.
    Harding, J.W., Stone, L.P. and Wright, J.W. (1981). Brain Res. 205: 265–274.PubMedCrossRefGoogle Scholar
  14. 14.
    Ji, H., Sandberg, D. and Catt, K.J. (1991). Mol. Pharmacol. 39: 120–123.PubMedGoogle Scholar
  15. 15.
    Murphy, T.J., Nakamura, Y., Takeuchi, K. and Alexander, R.W. (1993). Mol. Pharmacol. 44: 1–7PubMedGoogle Scholar
  16. 16.
    Sanberg, K., Ji, H., Clark, A.J.L., Shapira, H. and Catt, K.J. (1992). J. Biol. Chem. 267: 9455–9458.Google Scholar
  17. 17.
    Chaki, S. and Inagami, T. (1992). Biochem. Biophys. Res. Commun. 182: 388–394.PubMedCrossRefGoogle Scholar
  18. 18.
    Harding, J.W, Cook, V.I., Miller-Wing, A.V., Hanes, J.M., Sardinia, M.F., Hall, K.L., Stobb, J.W., Swanson, G.N., Coleman, J.K.M., Wright, J.W. and Harding, E.C. (1992). Brain Res. 583: 340–343.PubMedCrossRefGoogle Scholar
  19. 19.
    Bumpus, F.M., Catt, K.J., Chiu, A.T., de Gasparo, M., Goodfriend, M., Husain, T., Peach, A., Taylor, M.J. Jr. and Timmermans, P.B.M.W.M. (1991). Hypertension 17: 720–721.PubMedCrossRefGoogle Scholar
  20. 20.
    Speth, R.C. (1993). Regul. Pept. 44: 189–197.PubMedCrossRefGoogle Scholar
  21. 21.
    Heemskerk, F.M.J., Zorad, S., Seltzer, A. and Saavedra, J.M. (1993). NeuroReport 4: 103–105.PubMedCrossRefGoogle Scholar
  22. 22.
    de Oliveira, A.M., Viswanathan, M., Heemskerk, F.M.J., Correa, F.M.A. and Saavedra, J.M. (1994). Biochem. Biophys. Res. Commun. 200: 1049–1058.PubMedCrossRefGoogle Scholar
  23. 23.
    Viswanathan, M., de Oliveira, A.M., Correa, F.M.A. and Saavedra, J.M. (1994). Brain Res. 658: 265–270.PubMedCrossRefGoogle Scholar
  24. 24.
    Viswanathan, M., de Oliveira, A.M., Wu, R.M., Chiueh, C.C. and Saavedra, J.M. (1994). Cell. Molec. Neurobiol. 14: 99–104.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • J. M. Saavedra
    • 1
  • A. M. de Oliveira
    • 1
  • O. Jöhren
    • 1
  • M. Viswanathan
    • 1
  1. 1.Section on Pharmacology, Laboratory of Clinical ScienceNational Institute of Mental HealthBethesdaUSA

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