Skip to main content
SpringerLink
Log in
Book cover

Recent Advances in Cellular and Molecular Aspects of Angiotensin Receptors pp 153–165Cite as

Molecular Cloning of the Human AT2 Receptor

  • Chapter

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 396))

Abstract

The peptide hormone angiotensin II (AII), the biologically active component of the renin-angiotensin system, exerts a wide variety of physiological effects on the cardiovascular, endocrine and central and peripheral nervous system (1). AII exerts its physiological effects in the target tissues through specific interactions with plasma membrane receptors (2). Given the diversity of AII-mediated events and the differential signal transduction mechanisms, it has been proposed that multiple AII receptor subtypes exist (3,4).

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   169.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Peach, M.J. (1977). Physiol. Rev. 57: 313–370.

    PubMed  CAS  Google Scholar 

  2. Catt, K.J., Mendelsohn, F.A.O., Millan, M.A. and Aguilera, G. (1984). J. Cardiol. Pharmacol. 6: S575.

    Article  Google Scholar 

  3. de Gasparo, M., Whitebread, S., Mele, M., Motani, A.S., Whitcombe, P.J., Ramjoue, H.P. and Kamber, B.J. (1990). Cardiovasc. Pharmacol. 16: S31–S35.

    Article  Google Scholar 

  4. Hausdorff, W.P., Sekura, R.D., Aguilera, G. and Catt, K.J. (1987). Endocrinology 720: 1668–1678.

    Article  Google Scholar 

  5. Chiu, A.T., Herblin, W.F., McCall, D.E., Ardecky, R.J., Carini, D.J., Dunica, J.V., Pease, L.J., Wong, P.C., Wexler, R.C., Johnson, A.L. and Timmermans, P.B.M.W.M. (1989). 165: 196–203.

    Google Scholar 

  6. Whitebread, S., Mele, M., Kamber, B. and de Gasparo, M. (1989). Biochem. Biophys. Res. Commun. 163: 284–291.

    Article  PubMed  CAS  Google Scholar 

  7. Dudley, D.T., Panek, R.L., Major, T.C., Lu, G.H., Bruns, R.F., Klinkerus, B.A., Hodges, J.C. and Weishaar, R.E. (1990). Mol. Pharmacol. 38: 370–377.

    PubMed  CAS  Google Scholar 

  8. Chang, R.S.L., Lotti, V.J., Chen, T.B. and Faust, K.A. (1990). Biochem. Biophys. Res. Commun. 171: 813–817.

    Article  PubMed  CAS  Google Scholar 

  9. Zemel, S., Millan, M.A. and Aguilera, G. (1989). Endocrinology 124: 1774–1780.

    Article  PubMed  CAS  Google Scholar 

  10. Grady, E.F., Sechi, L.A., Griffin, C.A., Schambelan, M. and Kalinyak, J.E. (1991). J. Clin. Invest. 88: 921–933.

    Article  PubMed  CAS  Google Scholar 

  11. Sasaki, K., Yamano, Y., Bardhan, S., Iwai, N., Murray, J.J., Hasegawa, M., Matsuda, Y. and Inagami, T. (1991). Nature 351: 230–233.

    Article  PubMed  CAS  Google Scholar 

  12. Murphy, T.J., Alexander, R.W., Griendling, K.K., Runge, M.S. and Bernstein, K.E. (1991). Nature 351: 233–236.

    Article  PubMed  CAS  Google Scholar 

  13. Tsutsumi, K. and Saavedra, J.M. (1991). Am. J. Physiol. 261: H667–H670.

    PubMed  CAS  Google Scholar 

  14. Millan, M.A., Jacobowitz, D.M., Aguilera, G. and Catt, K.J. (1991). Proc. Natl. Acad. Sci. USA 88: 11440–11444.

    Article  PubMed  CAS  Google Scholar 

  15. Pucell, A.G., Hodges, J.C., Sen, I., Bumpus, F.M. and Husain A. (1991). Endocrinology 128: 1947–1959.

    Article  PubMed  CAS  Google Scholar 

  16. Kambayashi, Y., Bardhan, S., Takahashi, K., Tsuzuki, S., Inui, H., Hamakubo, T. and Inagami, T. (1993). J. Biol. Chem. 268: 24543–24546.

    PubMed  CAS  Google Scholar 

  17. Mukoyama, M., Nakajima, M., Horiuchi, M., Sasamura, H., Pratt, R.E. and Dzau, V.J. (1993). J. Biol. Chem. 268: 24539–24542.

    PubMed  CAS  Google Scholar 

  18. Nakajima, M., Mukoyama, M., Pratt, R.E., Horiuchi, M. and Dzau, V.J. (1993). Biochem. Biophys. Res. Commun. 197: 393–399.

    Article  PubMed  CAS  Google Scholar 

  19. Bottari, S.P., Taylor, V., King, I.N., Bogdal, Y., Whitebread, S. and de Gasparo, M. (1991). Eur. J. Pharmacol. 207: 157–163.

    Article  PubMed  CAS  Google Scholar 

  20. Dudley, D.T., Hubbell, S.E. and Summerfelt, R.M. (1991). Mol. Pharmacol. 40: 360–367.

    PubMed  CAS  Google Scholar 

  21. Leung, K.H., Roscoe, W.A., Smith, R.D., Timmermans, P.B.M.W.M. and Chiu, A.T. (1992). Eur. J. Pharmacol. 227: 63–70.

    Article  PubMed  CAS  Google Scholar 

  22. Jaiswal, N., Tallant, E.A., Diz, D.I., Khosla, M.C. and Ferrario, C.M. (1991). Hypertension 17: 1115–1120.

    Article  PubMed  CAS  Google Scholar 

  23. Buisson, B., Bottari, S.P., de Gasparo, M., Gallo, P.N. and Payet, M.D. (1992). FEBS Lett. 309: 161–164.

    Article  PubMed  CAS  Google Scholar 

  24. Sumners, C., Tang, W., Zelezna, B. and Raizada, M.K. (1991). Proc. Natl. Acad. Sci. USA 88: 7567–7571.

    Article  PubMed  CAS  Google Scholar 

  25. Bottari, S.P., King, I.N., Reichlin, S., Dahlstroem, I., Lydon, N. and de Gasparo, M. (1992). Biochem. Biophys. Res. Commun. 183: 206–211.

    Article  PubMed  CAS  Google Scholar 

  26. Brechler, V., Levens, N.R., de Gasparo, M. and Bottari, S.P. (1993). Regul. Peptides 44: 207–213.

    Article  CAS  Google Scholar 

  27. Takahasi, K., Bardhan, S., Kambayashi, Y., Shirai, H. and Inagami, T. (1994). Biochem. Biophys. Res. Commun. 198: 60–66.

    Article  PubMed  CAS  Google Scholar 

  28. Bottari, S.P., de Gasparo, M., Steckelings, U.M. and Levens, N.R. (1993). Front. Neuroendo. 14: 123–171.

    Article  CAS  Google Scholar 

  29. Martin, M.M., Su, B. and Elton, T.S. (1994). Biochem. Biophys. Res. Commun. 205: 645–651.

    Article  PubMed  CAS  Google Scholar 

  30. Kemp, B.E. and Pearson, R.B. (1990). Trends Biochem. Sci. 15: 342–346.

    Article  PubMed  CAS  Google Scholar 

  31. Hubbard, S.C. and Ivatt, R.J. (1981). Annu. Rev. Biochem. 50: 555–583.

    Article  PubMed  CAS  Google Scholar 

  32. Servant, G., Dudley, D.T., Escher, E. and Guillemette, G. (1994). Mol. Pharmacol. 45: 1112–1118.

    PubMed  CAS  Google Scholar 

  33. Guo, D., Furata, H., Mizukoshi, M. and Inagami, T. (1994). Biochem. Biophys. Res. Commun. 200: 313–319.

    Article  PubMed  CAS  Google Scholar 

  34. Su, B., Martin, M.M., Beason, K.B., Miller, P.J. and Elton, T.S. (1994). Biochem. Biophys. Res. Commun. 204: 1039–1046.

    Article  PubMed  CAS  Google Scholar 

  35. Takeuchi, K., Alexander, R.W., Nakamura, Y., Tsujino, T. and Murphy, T.J. (1993). Circ. Res. 73: 612–621.

    Article  PubMed  CAS  Google Scholar 

  36. Guo, D.F. and Inagami, T. (1994). Biochim. et Biophys. Acta 1218: 91–94.

    Article  CAS  Google Scholar 

  37. Ichiki, T., Herold, CL., Kambayashi, Y., Bardhan, S. and Inagami, T. (1994). Biochim. et Biophys. Acta 1189: 247–250.

    Article  CAS  Google Scholar 

  38. Tsuzuki, S., Ichiki, T., Nakakubo, H., Kitami, Y., Guo, D., Shirai, H. and Inagami, T. (1994). Biochem. Biophys. Res. Commun. 200: 1449–1454.

    Article  PubMed  CAS  Google Scholar 

  39. Koike, G., Horiuchi, M., Yamada, T., Szpirer, C., Jacob, H.J. and Dzau, V.J. (1994). Biochem. Biophys. Res. Commun. 203: 1842–1850.

    Article  PubMed  CAS  Google Scholar 

  40. Martin, M.M. and Elton, T.S. Biochem. Biophys. Res. Commun. (1995, in press).

    Google Scholar 

  41. Csank, C., Taylor, F.M. and Martindale, D.W. (1990). Nucleic Acids Res. 18: 5133–5141.

    Article  PubMed  CAS  Google Scholar 

  42. Xu, L., Thali, M. and Schaffner, W. (1991). Nucleic Acids Res. 19: 6699–6704.

    Article  PubMed  CAS  Google Scholar 

  43. Ghosh, D. (1990). Nucleic Acids Res. 18: 1749–1756.

    Article  PubMed  CAS  Google Scholar 

  44. Morgan, W.D., Williams, G.T., Morimoto, R.I., Greene, J., Kingston, R.E. and Tjian, R. (1987). Mol. Cell. Biol. 7: 1129–1138.

    PubMed  CAS  Google Scholar 

  45. Akira, S., Isshiki, H., Sugita, T., Tanabe, O., Kinoshita, S., Nishio, Y., Nakajima, T., Hirano, T. and Koshimoto, T. (1990). EMBO J. 9: 1897–1906.

    PubMed  CAS  Google Scholar 

  46. Wasylyk, C., Flores, P., Gutman, A. and Wasylyk, B. (1989). EMBO J. 5: 3371–3378.

    Google Scholar 

  47. Wasylyk, B., Wasylyk, S., Flores, P., Beque, A.I., Leprinc, D. and Stehelin, D. (1990). Nature 346: 191–193.

    Article  PubMed  CAS  Google Scholar 

  48. Kadonaga, J.T., Carner, K.R., Mariarz, F.R. and Tjian, R. (1987). Cell 51: 1079–1090.

    Article  PubMed  CAS  Google Scholar 

  49. Chiu, R., Imugawa, M., Imbra, R.J., Bockoven, J.R. and Karin, M. (1987). Nature 329: 648–651.

    Article  PubMed  CAS  Google Scholar 

  50. Majello, B., Arcone, R., Toniatti, C. and Ciliberto, G. (1990). EMBO J. 9: 457–465.

    PubMed  CAS  Google Scholar 

  51. Wall, L., deBoer, E. and Grosveld, F. (1988). Genes and Develop. 2: 1089–1100.

    Article  CAS  Google Scholar 

  52. Driggers, P.H., Ennist, D.L., Gleason, S.L., Mak, W.H., Marks, M.S., Levi, B.Z., Flanagan, J.R., Appella, E. and Ozato, K. (1990). Proc. Natl. Acad. Sci. USA 87: 3743–3747.

    Article  PubMed  CAS  Google Scholar 

  53. Tsukiyama, T., Ueda, H., Hirose S. and Niwa, O. (1992). Mol. Cell. Biol. 12: 1286–1291.

    PubMed  CAS  Google Scholar 

  54. Tsukiyama, T., Niwa, O., and Yokoro, K. (1989). Mol. Cell. Biol. 9: 4670–4676.

    PubMed  CAS  Google Scholar 

  55. Grone, H.J., Simon, M. and Fuchs, E. (1992). Am. J. Physiol. 262: F326–F331.

    PubMed  CAS  Google Scholar 

  56. Nahmias, C., Cazaubon, S.M., Briend-Sutren, M.M., Lazard, D., Villageois, P. and Strosberg, A.D. (1995). Biochem. J. 306: 87–92.

    PubMed  CAS  Google Scholar 

  57. Dudley, D.T. and Summerfelt, R.M. (1993). Reg. Peptides 44: 199–206.

    Article  CAS  Google Scholar 

  58. Kambayashi, Y., Bardhan, S. and Inagami, T. (1993). Biochem. Biophys. Res. Commun. 194: 478–482.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry and Biochemistry, Benson Science Building, Brigham Young University, Provo, Utah, 84602, USA

    Mickey M. Martin, Baogen Su & Terry S. Elton

Authors
  1. Mickey M. Martin
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Baogen Su
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Terry S. Elton
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of Florida, Gainesville, Florida, USA

    Mohan K. Raizada , M. Ian Phillips  & Colin Sumners ,  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Springer Science+Business Media New York

About this chapter

Cite this chapter

Martin, M.M., Su, B., Elton, T.S. (1996). Molecular Cloning of the Human AT2 Receptor. In: Raizada, M.K., Phillips, M.I., Sumners, C. (eds) Recent Advances in Cellular and Molecular Aspects of Angiotensin Receptors. Advances in Experimental Medicine and Biology, vol 396. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1376-0_16

Download citation

  • DOI: https://doi.org/10.1007/978-1-4899-1376-0_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1378-4

  • Online ISBN: 978-1-4899-1376-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation