Skip to main content

New Saponins from Vietnamese Ginseng: Highlights on Biogenesis of Dammarane Triterpenoids

  • Chapter
Book cover Saponins Used in Traditional and Modern Medicine

Abstract

Panax ginseng C. A. Meyer (ginseng) and its two congeners, P. notoginseng (Burk.) F. H. Chen (Sanchi ginseng) and P. quinquefolium L. (American ginseng), are well-known plant drugs which have been widely used in many countries of the world, especially in Asia and North America. These are now cultivated plants, differentiating them from a variety of wild Panax spp., which are morphologically related and distributed from Japan to the Eastern Himalayas. Comparative studies on the saponin composition of P. ginseng and other Panax spp. have been elaborated extensively in view of pharmacological and chemotaxonomical interest.1,2

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. a) O. Tanaka, and R. Kasai, Saponins of ginseng and related plants, in: Fortschritte der Chemie Organischer Naturstoffe, Vol. 46, W. Hertz, H. Grisebach, G. W. Kirby, and Ch. Tatum, eds., Springer-Verlag, Wien, New York, (1984); b) O. Tanaka, R. Kasai, and T. Morita, Chemistry of ginseng and related plants: recent advances, Abstracts of Chinese Medicines (The Chinese University of Hong Kong), 1:130 (1986); c) O. Tanaka, Recent studies on glycosides from plant drugs of Hymalaya and southwestern China. Chemo-geographical correlation of Panax species, Pure and Appl. Chem., 62:1281 (1990).

    Google Scholar 

  2. S. Shibata, O. Tanaka, J. Shoji, and H: Saito, Economic and Medicinal Plant Research, Vol. I, Academic Press, Inc. ( London) Ltd., (1985).

    Google Scholar 

  3. D. K. Long, Information about a new Panax species discovered in Kon Turn province of Vietnam, unpublished document of the Fifth Zone Health Service of Vietnam (1973).

    Google Scholar 

  4. H. T. Dung, and I. V. Grushvitsky, Panax vietnamensis, a new Panax species, J. Vietnam Bot., 4: 518 (1985).

    Google Scholar 

  5. N. T. Nham, P. V. De, T. C. Luan, N. M. Duc, S. Shibata, O. Tanaka, and R. Kasai, Pharmacognostical and chemical studies on Vietnamese ginseng, Panax vietnamensis Ha et Grushv. (Araliaceae), J. Japn. Bot., 70: 1 (1995).

    Google Scholar 

  6. T. Takemoto, S. Akihara, T. Nakajima, and M. Okuhira, Studies on the constituents of Gymnostemma pentaphyllum Makino. II. Structure of gypenosides XV - XXI, Yakugaku Zasshi, 103: 1015 (1983).

    CAS  Google Scholar 

  7. R. Nie, T. Morita, R. Kasai, J. Zhou, C-Y. Wu, and O. Tanaka, Saponin from Chinese medicinal plants. (1). Isolation and structures of hemslosides, Planta Med., 50: 322 (1984).

    Article  PubMed  CAS  Google Scholar 

  8. N. M. Duc, N. T. Nham, R. Kasai, A. Ito, K. Yamasaki, and O. Tanaka, Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. collected in central Vietnam. I., Chem. Pharm. Bull., 41: 2010 (1993).

    Google Scholar 

  9. N. M. Duc, R. Kasai, K. Ohtani, A. Ito, N. T. Nham, K. Yamasaki, and O. Tanaka, Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. collected in central Vietnam. II., Chem. Pharm. Bull., 42: 115 (1994).

    Article  Google Scholar 

  10. N. M. Duc, R. Kasai, K. Ohtani, A. Ito, N. T. Nham, K. Yamasaki, and O. Tanaka, Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. collected in central Vietnam. III. Chem. Pharm. Bull., 42: 634 (1994).

    Article  PubMed  CAS  Google Scholar 

  11. J. Asakawa, R. Kasai, K. Yamasaki, and O. Tanaka, 13C NMR study of ginseng sapogenins and their related dammarane type triterpenes, Tetrahedron, 33: 1935 (1977).

    Google Scholar 

  12. T. Morita, R. Kasai, O. Tanaka, J. Zhou, T. R. Yang, and S. Shoji, Saponins of Zu-tziseng, rhizomes of Panax japonicus C. A. Meyer var. major (Burk.) C. Y. Wu et K. M. Feng, collected in Yunnan, China, Chem. Pharm. Bull., 30: 4341 (1982).

    Article  CAS  Google Scholar 

  13. H. Matsuura, R. Kasai, O. Tanaka, Y-I. Saruwatari, T. Fuwa, and J. Zhou, Futher studies on dammarane saponins of Sanchi-ginseng, Chem. Pharm. Bull., 31: 2281 (1983).

    Article  CAS  Google Scholar 

  14. H. Budzikiewics, C. Djerassi, and D. H. Williams, Structure Elucidation of Natural Products by Mass Spectrometry, Holden-Day Inc., San Francisco (1964).

    Google Scholar 

  15. C. R. Enzell, R. A. Apleton, and I. Wahlberg, Terpenes and terpenoids, in: Biochemical Applications of Mass Spectrometry, G. R. Waller, ed., John Wiley and Sons, Inc., New York, London, Sidney, Canada (1972).

    Google Scholar 

  16. O. Tanaka, and S. Yahara, Dammarane saponins of leaves of Panax pseudo-ginseng subsphimalaicus, Phytochemistry, 17: 1353 (1978).

    Article  CAS  Google Scholar 

  17. C. Matsubara, and A. Romo de Vivar, Tetracyclic triterpenes from Parthenium fruticosum, Phytochemistry, 24: 613 (1985).

    Article  CAS  Google Scholar 

  18. S. Fujita, K. Ohtani, R. Kasai, and K. Yamasaki, unpublished data (1994).

    Google Scholar 

  19. M. L. Vickery, and B. Vickery, Secondary Plant Metabolism, MacMillan Press Ltd., (1981).

    Google Scholar 

  20. S. Yahara, The Chemical Study on the Sâponin Composition of the Leaves of Panax spp. ( Ph.D. thesis ), Hiroshima University (1978).

    Google Scholar 

  21. S. Shibata, M. Fujita, H. Itokawa, O. Tanaka, and T. Ishii, Studies on the constituents of Japanese and Chinese crude drugs. XI. Panaxadiol, a sapogenin of ginseng roots, Chem. Pharm. Bull., 11: 759 (1963).

    Article  PubMed  CAS  Google Scholar 

  22. S. Shibata, O. Tanaka, M. Nagai, and T. Ishii, Studies on the constituents of Japanese and Chinese crude drugs. XII. Panaxadiol, a sapogenin of ginseng roots. (2)., Chem. Pharm. Bull., 11: 762 (1963).

    Article  PubMed  CAS  Google Scholar 

  23. S. Shibata, O. Tanaka, T. Ando, M. Sado, T. Tsushima, and T. Ohsawa, Chemical studies on oriental plant drugs. XIV. Protopanaxadiol, a genuine sapogenin of ginseng saponins, Chem. Pharm. Bull., 14: 595 (1966).

    Article  PubMed  CAS  Google Scholar 

  24. S. Fujita, R. Kasai, K. Ohtani, K. Yamasaki, C. Ming-Hua, N. Rui-Lin, and O. Tanaka, Dammarane glycosides from aerial part of Neoalsomitra integrifoliola, Phytochemistry, 39: 591 (1995).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Springer Science+Business Media New York

About this chapter

Cite this chapter

Duc, N.M. et al. (1996). New Saponins from Vietnamese Ginseng: Highlights on Biogenesis of Dammarane Triterpenoids. In: Waller, G.R., Yamasaki, K. (eds) Saponins Used in Traditional and Modern Medicine. Advances in Experimental Medicine and Biology, vol 404. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1367-8_13

Download citation

  • DOI: https://doi.org/10.1007/978-1-4899-1367-8_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1369-2

  • Online ISBN: 978-1-4899-1367-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics