Cytokines and Tumor Immunogenicity

Toward an Appropriate Cancer Vaccine
  • Federica Cavallo
  • Katia Boggio
  • Mirella Giovarelli
  • Guido Forni
Part of the Pezcoller Foundation Symposia book series (PFSO, volume 9)

Abstract

Molecular biology and genetics are currently providing a definition of tumor-associated antigens (TAA). This important issue enables the question of immune recognition of tumors be stated in defined terms. Immunological investigation of T lymphocyte receptor, costimulatory molecules, signal transduction and cytokines has progressively led to a much more exact description of the requirements for the induction of an immune response. Refinement of cell genetic engineering is making it almost daily easier to use molecular and genetic information to construct new cancer vaccines. The convergence of these issues is once again placing tumor immunology at the cutting edge of biological research1,2.

Keywords

Adenocarcinoma Sarcoma Interferon Myeloma Hunt 

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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Federica Cavallo
    • 1
  • Katia Boggio
    • 1
  • Mirella Giovarelli
    • 1
  • Guido Forni
    • 1
  1. 1.Dipartimento di Scienze Cliniche e BiologicheUniversity of TurinOrbassanoItaly

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