Clinical Applications of Stereotactic Radiosurgery

  • Richard P. Levy
  • Jacob I. Fabrikant

Abstract

The concept of stereotactic radiosurgery was introduced in 1951 by Leksell [58] to describe a technique developed to create small, well-defined lesions in the brain using stereotactically-directed narrow beams of ionizing radiation. Stereotactic radiosurgery may be characterized as a clinical external-beam radiation-treatment procedure applied to a relatively small volume of intracranial tissue in which the total radiation dose is delivered stereotactically through multiple discrete entry portals or arcs in a single or limited number of fractions; the intent is to damage a designated population of cells within the target volume, while protecting the adjacent normal tissues (Table 6.1). The radiosurgical approach is contrasted with conventional external-beam radiotherapy, which generally involves treatment of a larger tissue volume in which the total dose is delivered in a relatively large number of small daily increments over a period of weeks; here, the intent is to destroy the reproductive capacity of neoplastic cells (Table 6.1).

Keywords

Adenoma Shrinkage Fractionation Oncol Neurol 

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Richard P. Levy
  • Jacob I. Fabrikant

There are no affiliations available

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