Advertisement

Iodine and Goitre in the Netherlands a Role for Nitrate Pollution?

  • Daan van der Heide
  • Janny P. Schröder-van der Elst
Chapter
Part of the NATO ASI Series book series (NSSA, volume 241)

Abstract

Iodized salt was introduced in The Netherlands in 1928 and the use was voluntary. In 1968 this preventive measure was replaced by the introduction of iodized bread salt. This salt was used by bakers in bread and contained 46 mg KI per kg salt. It became mandatory all over the country. The iodized salt (3–8 mg KI/kg) remained available for voluntary use. In 1974 the Ministery of Public Health decided that the iodized household salt was no longer necessary and the sale was stopped. During the seventies the consumption of bread per capita decreased. An epidemiological survey on goitre prevalence and urinary iodine excretion was carried out in 1976 by Tan et al1. The main conclusion of this studie was that the existing level of iodine supplementation was insufficient to prevent endemic goitre especially in female adolescents. Based on these results a Committee of the National Health Board (1981) advised a revision of the goitre profylaxis measures1, which were executed in 1982. Iodized household salt with a higher iodine content (23–29 mg KI/kg) was reintroduced and the iodine content of bread salt was raised from 46 to 60 mg KI per kg. In order to assess the effect of these revisions epidemiological surveys were carried out

Keywords

Iodine Content Endemic Goitre Urinary Iodine Excretion Goitre Prevalence Iodine Supplementation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Gezondheidsraad. “Advies Inzake Jodiumvoorziening. Rapport no 78”. Gezondheidsraad, Gravenhage, The Netherlands(1981).Google Scholar
  2. 2.
    M.M. van Rees-Wortelboer, J.P. Schröder- van der Eist, A. Lycklama, and D. van der Heide, Jodium en krop in Nederland. Ned Tijdschr Geneesk. l31:1821 (1987).Google Scholar
  3. 3.
    J. Brug, M.N.H. Löwik, J.J. van Binsbergen, J. Odink, NJ. Egger, and M. Wedel, Indication of iodine status among adults (Dutch Nutrition Surveillance System), Ann. Nutrit. Metab. in press(1992).Google Scholar
  4. 4.
    J.T. Dunn, and G.A. Medeiros-Neto. “Endemic Goiter and Cretinism: Continuing Threats to World Health. PAHO Scientific Publication 292”, Pan American Health Organization, Washington (1974).Google Scholar
  5. 5.
    J.B. Wyngaarden, J.B. Stanbury, and B. Rapp, The effects of iodide, perchlorate, thiocyanate and nitrate administration upon the iodide concentrating mechanism of the rat thyroid, Endocrinology 52:568 (1953).PubMedCrossRefGoogle Scholar
  6. 6.
    R.A. Bloomfield, C.W. Welsch, G.B. Garner, and M.P. Muhrer, Effect of dietary nitrate on thyroid function, Science. 134:1690 (1961).PubMedCrossRefGoogle Scholar
  7. 7.
    D. Knopp, J. Buschmann, J. Höring, M. Gottschalk, and W. Seffner, Veränderung von funktion und morphologie der ratten Schilddrüse nach oraler nitrat-verab-reichung, Z. Gesamte Hyg. 29: 664 (1983).PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Daan van der Heide
    • 1
  • Janny P. Schröder-van der Elst
    • 2
  1. 1.Department of Human and Animal PhysiologyAgricultural UniversityWageningenThe Netherlands
  2. 2.Department of EndocrinologyUniversity HospitalLeidenThe Netherlands

Personalised recommendations