Challenges in the Genetic Epidemiology of Insulin-Dependent Diabetes Mellitus
The advances in human genetics and molecular biology during the last decades have provided new opportunities for a better understanding of the genetic and molecular susceptibility to many diseases of complex aetiology, including insulin-dependent diabetes mellitus (IDDM). This is illustrated by the almost exploding number of publications dealing with new genetic and molecular markers of IDDM. As a consequence of this development, a new front, the molecular epidemiology of IDDM, has emerged in the efforts to unravel the aetiology of IDDM.
KeywordsGenetic Marker Segregation Analysis Complex Aetiology Disease Susceptibility Gene Disease Determinant
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