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Case-Control Molecular Epidemiology Studies: Standards for the WHO DIAMOND Project

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Standardization of Epidemiologic Studies of Host Susceptibility

Part of the book series: NATO ASI Series ((NSSA,volume 270))

Abstract

The development of standardized incidence registries has led to one of the most striking epidemiologic findings regarding IDDM. Unlike most other chronic childhood diseases, there is more than a 30-fold difference in incidence across populations, with the rates being very high in Scandinavian countries, such as Finland, but very low in the Oriental populations, such as Korea and Japan.1 Among Caucasians, there is also marked variability in the annual incidence of IDDM. Rates are much lower in the central and southern parts of Europe, such as France and Italy, than in northern Europe.2,3 In addition, major racial differences in incidence within populations have been reported, where Caucasians consistently have higher rates of IDDM than African Americans from the same geographically-defined area.3

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Authors and Affiliations

  1. Department of Epidemiology Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, 15261, USA

    Janice S. Dorman, Leslie A. O’Leary & Mary Kaye Kramer

  2. Department of Pediatrics Division of Immunogenetics, Children’s Hospital of Pittsburgh, Pittsburgh, PA, 15213, USA

    Mirjana Kocova & Massimo Trucco

Authors
  1. Janice S. Dorman
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  2. Mirjana Kocova
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  3. Leslie A. O’Leary
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  4. Mary Kaye Kramer
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  5. Massimo Trucco
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Editors and Affiliations

  1. Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

    Janice S. Dorman

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© 1994 Springer Science+Business Media New York

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Dorman, J.S., Kocova, M., O’Leary, L.A., Kramer, M.K., Trucco, M. (1994). Case-Control Molecular Epidemiology Studies: Standards for the WHO DIAMOND Project. In: Dorman, J.S. (eds) Standardization of Epidemiologic Studies of Host Susceptibility. NATO ASI Series, vol 270. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1213-8_14

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  • DOI: https://doi.org/10.1007/978-1-4899-1213-8_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1215-2

  • Online ISBN: 978-1-4899-1213-8

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