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Synthesis of Organofluorine Compounds

  • R. E. Banks
  • J. C. Tatlow
Part of the Topics in Applied Chemistry book series (TAPP)

Abstract

Fluoroorganic chemistry is virtually a man-made subject. Indeed, perfluorocarbon chemistry—which straddles organic and inorganic chemistry—is sometimes facetiously referred to as unnatural product chemistry. Fluorometabolites do occur in nature, but they are few in number and only monofluorides have been detected so far.1 The best known is the plant metabolite CH2FCO2H (see Chapter 1); the other nine include the related compounds CH2FCOCH3, 2-fluorocitric acid, F(CH2) n CO2H (n = 9, 13, 15), and F(CH2)8CH=CH(CH2)7CO2H. The most intriguing by far is nucleo-cidin (1), an antibiotic fluoro-sugar derivative produced by the microorganisms Streptomyces calvus.

Keywords

Mechanistic Category Dipolar Aprotic Solvent Fluorine Chemistry Organofluorine Compound Fluorinating Agent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • R. E. Banks
    • 1
  • J. C. Tatlow
    • 2
  1. 1.Department of ChemistryThe University of Manchester Institute of Science and TechnologyManchesterEngland
  2. 2.Editorial Office of the Journal of Fluorine ChemistryBirminghamEngland

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