Abstract
Connective tissue diseases have a predilection for the female sex and often affect women of childbearing age. The concurrence of pregnancy and connective tissue disease may represent a hazard both to mother and child. Underlying disease processes will add to the physiological changes of pregnancy and in some cases aggravate symptoms in the pregnant patient. This is a risk in systemic lupus erythematosus (SLE), mixed connective tissue disease (MCTD), and progressive systemic sclerosis (PSS). On the other hand, the fetus may be affected by maternal systemic disease and/or vasculopathy of the placenta associated with connective tissue disease. Placental transfer of maternal autoantibodies may cause neonatal disease from SLE (Lockshin, 1985). Thus both patient and clinician have to face special demands resulting from the interaction between pregnancy and a complex disease process.
Keywords
- Systemic Lupus Erythematosus
- Breast Milk
- Systemic Lupus Erythematosus Patient
- Human Milk
- Congenital Malformation
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Østensen, M. (1992). Immunopharmacological Treatment during Pregnancy and Lactation. In: Rugstad, H.E., Endresen, L., Førre, Ø. (eds) Immunopharmacology in Autoimmune Diseases and Transplantation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1167-4_19
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