Amino Acid Transport in Intestine

  • Bruce R. Stevens


During the past 30 years many of the universal principles of membrane transport have been established or confirmed using the readily accessible and testable small intestine. Historically, amino acid transport studies have been conducted in a variety of species at various stages of ontogenetic development. The intact epithelium, isolated enterocytes, and isolated brush border and basolateral membranes have each been used to investigate the physiologic, thermodynamic and kinetic events of absorption. Recently, our laboratory (Pan et al., 1991) and others (Hidalgo & Borchardt, 1990) have used cultured intestinal cell lines to study amino acid transport regulation in monolayers that emulate the in vivo epithelium (Zweibaum et al., 1991).


Brush Border Basolateral Membrane Amino Acid Transport Brush Border Membrane Amino Acid Uptake 
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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Bruce R. Stevens
    • 1
  1. 1.Department of Physiology, College of MedicineUniversity of FloridaGainesvilleUSA

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