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Transformation by Polyomaviruses

Role of Tumor Suppressor Proteins
  • Daniel T. Simmons
Part of the Infectious Agents and Pathogenesis book series (IAPA)

Abstract

Since its identification as a tumor virus, SV40 has been a favorite model for understanding the mechanism by which a DNA virus can control the state and growth properties of susceptible cells. From its humble beginnings, the polyomavirus tumor biology field has mushroomed into several new directions, most notably into tumor suppressors. These new branches are now buzzing with activity and touching or merging with other established disciplines including cell-cycle controls, oncogenes, and differentiation.

Keywords

Tumor Suppressor Protein Simian Virus Polyoma Virus Retinoblastoma Gene Product Large Tumor Antigen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Daniel T. Simmons
    • 1
  1. 1.Department of BiologyUniversity of DelawareNewarkUSA

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