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Chromatographic Techniques for the Characterization of Proteins

  • Chapter
Physical Methods to Characterize Pharmaceutical Proteins

Part of the book series: Pharmaceutical Biotechnology ((PBIO,volume 7))

Abstract

The improvements in the Chromatographic analysis of proteins and peptides during the last decade contributed significantly to the development of (recombi-nant) pharmaceutical proteins. The availability of these analytical methods for the characterization and purity determination of proteins enabled the improvement of the overall manufacturing process of pharmaceutical proteins.

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Authors and Affiliations

  1. OctoPlus b. v., P.O. Box 722, 2300 AS, Leiden, The Netherlands

    Joost J. M. Holthuis

  2. Ares Serono, Chemin des Mines, CH-1211, Geneva, Switzerland

    Reinoud J. Driebergen

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  1. Joost J. M. Holthuis
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  2. Reinoud J. Driebergen
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  1. University of Utah, Salt Lake City, Utah, USA

    James N. Herron

  2. National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands

    Wim Jiskoot

  3. Groningen-Utrecht Institute for Drug Exploration, Utrecht University, and Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands

    Daan J. A. Crommelin

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Holthuis, J.J.M., Driebergen, R.J. (1995). Chromatographic Techniques for the Characterization of Proteins. In: Herron, J.N., Jiskoot, W., Crommelin, D.J.A. (eds) Physical Methods to Characterize Pharmaceutical Proteins. Pharmaceutical Biotechnology, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1079-0_7

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  • DOI: https://doi.org/10.1007/978-1-4899-1079-0_7

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