Scale-Up from Laboratory to Plant

  • Edward J. Griffith
Part of the Topics in Applied Chemistry book series (TAPP)


Very often scale-up from laboratory to pilot plant or full-size manufacturing plant can present many challenges that are not easily resolved. It is in this domain that chemical engineers make their greatest contribution to new progress. Chemists, more than engineers, are inclined to be artistic rather than practical. They often build art-forms of science for the archives rather than useful products for the everyday world. (I take license in this statement because I am a chemist and not an engineer.)


Sugar Burner Phosphorus Corn Graphite 


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  1. 1.
    E. J. Griffith and C. E. Callis, J. Am. Chem. Soc. 81, 833 (1959).CrossRefGoogle Scholar
  2. 2.
    J. R. Van Wazer, Phosphorus and Its Compounds, p. 515, Interscience, New York (1958).Google Scholar
  3. 3.
    T. C. Miller, Calcium Oxide and Water, National Gypsum Company, Buffalo, New York (1961).Google Scholar
  4. 4.
    E. J. Griffith, J. R. Jany, and T. M. Ngo, U.S. Patent 4,717,487 (January 5, 1988 ).Google Scholar
  5. 5.
    I. Motooka and M. Kobayashi, in Topics in Phosphorus Chemistry, Vol. 10 ( M. Grayson and E. J. Griffith, eds.), p. 171, Wiley, New York (1980).Google Scholar

Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Edward J. Griffith
    • 1
  1. 1.Monsanto CompanySt. LouisUSA

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