Industrial Fermentation and Aspergillus Citric Acid

  • A. G. Brooke
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 69)

Abstract

Citric acid (2-hydroxy-l, 2, 3-propanetricarboxylic acid) was first isolated from lemon juice by the Swedish chemist Scheele (1784), and first produced commercially by John and Edmund Sturge in England from 1823 onwards. Production was from Italian produced calcium citrate derived from lemon and lime juice from Martinique. Before the end of the century, this production method had also been established in France and Germany. However, by 1920 the Italians had also begun to produce citric acid themselves, establishing a monopoly with concomitant high prices. As a result alternative methods of citric acid production were sought.

Keywords

Fermentation Aspirin Pyruvate Lime Gypsum 

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References

  1. Binot, R., Bol, T., Naveau, H-P. and Nyns, E-J. (1982) Biomethanation by immobilised fluidised cells. IAW PR Specialised Seminar Copenhagen, Denmark.Google Scholar
  2. Braun, R., Meyrath, J., Stuparek, W. and Zerlauth, G. (1979) Feed yeast production from citric acid waste. Pr ocess Biochem, 14 (1) 16–20.Google Scholar
  3. Clark, D. S. (1964) (National Research Council of Canada, Citric acid production, US Pat. 3 118 821. Chem Abstr., 61 4926d.Google Scholar
  4. Clark, D. S., Ito, K. and Horitsu, H. (1966). Effect of manganese and other heavy metals on submerged fermentation of molasses. Biotechnol Bioeng., 8, 455–471.CrossRefGoogle Scholar
  5. Currie, J. N. (1917) The citric acid fermentation of A. niger. J Biol. Chem., 31, 15–17Google Scholar
  6. De Zeeuw, W. J. and Lettinga, G. (1980) Use of anaerobic digestion for waste water treatment. Antonie van Leeuwenhoek, 46, 110–112.PubMedCrossRefGoogle Scholar
  7. Doulger, W. P. and Prescot, S. C. (1939) Citric acid fermentation. Ind. Eng. Chem., 26 1142–1149.CrossRefGoogle Scholar
  8. Grimoux, E and Adam, P. (1880) Synthase de l’acide citrique. C. R. Hebd Seance Acad Sci., 90, 1252–1255Google Scholar
  9. Hustede, H. and Rudy, H. (1976a) Manufacture of citric acid by submerged fermentation. US Pat 3 941 656. Chem. Abstr., 84 178–222w. (J. A. Benckiser ed.).Google Scholar
  10. Hustede, H. and Rudy, H. (1976b) Manufacture of citric acid by submerged fermentation. US Pat. 3 940 315. Chem. Abstr., 85, 3869f. (J. A. Benckiser ed.).Google Scholar
  11. Kisser, M., Kubicek, C. P. and Rohr, M. (1980) Influence of manganese on morphologyand cell wall composition of A. niger during citric acid fermentation. Arch. Microbiol, 128, 26–33.PubMedCrossRefGoogle Scholar
  12. Kubicek, P. and Rohr. (1980) Citric acid fermentation. CRC Critical Review of Biotech., 3, 331–373.CrossRefGoogle Scholar
  13. Les Usines de Melle (1961) Process for extracting citric acid from aqueous solutions thereof. Br. Pat. 874030. Chem. Abstr., 55 18010c.Google Scholar
  14. Les Usine de Melle (1963) Process for extracting citric carboxylic acids produced by fermentation. Br. Pat. 936 339 Chem. Abstr. 57, 15620a.Google Scholar
  15. Perlman, D. (1949) Mycological production of citric acid — the submerged culture method. Econ. Bot., 3, 360–374.CrossRefGoogle Scholar
  16. Pfizer Inc. (1974) Fermentation process for the production of citric acid. Br. Pat. 1 364 094. Chem. Abstr. 78, 70192y.Google Scholar
  17. Snell, R. L. and Schweig, B. (1951) Citric acid by fermentation, Br. Pat. 653 808. Chem. Abstrc. 45 8719aGoogle Scholar
  18. Stottmeister, U., Behrens, U., Weissbrodt, E., Barth, G., Franke-Rinker, D. and Schulze, E. (1982) Nutzumg von Paraffinen und anderen Nichtkohlenhydrate — Kohlenstoffquellan zur mikrobiellen Citronensaure Synthese. Z. Allg. Mikrobiol., 22, 399–424.PubMedCrossRefGoogle Scholar
  19. Wehmer, C. (1893) Note sur fermentation citrique. Bull Soc. Chim. Fr., 9, 728–730.Google Scholar

Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • A. G. Brooke
    • 1
  1. 1.Haarmann & ReimerSelby, North YorkshireUK

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