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Cardiovascular and Neuroendocrine Responses to Challenge in Males and Females

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Abstract

Increasing attention has been given to the role that physiological response to behavioral challenges, i. e., Stressors, may play in the development of cardiovascular disease (see Matthews et al., 1986). Behavioral Stressors typically evoke notable cardiovascular and neuroendocrine responses. To date, preliminary evidence from the literature on both Type A behavior pattern (TABP) and essential hypertension implicates the role of behaviorally induced sympathetically mediated cardiovascular and neuroendocrine responses to mildly challenging Stressors in the subsequent development of disease (for a thorough review, see Krantz & Manuck, 1984).

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References

  • Abplanalp, J. M., Livingston, L., Rose, R. M., & Sandwisch, D. (1977). Cortisol and growth hormone responses to psychological stress during the menstrual cycle. Psychosomatic Medicine, 39, 158–177.

    PubMed  CAS  Google Scholar 

  • Adams, S., Williams, V., & Vessey, M.P. (1981). Cardiovascular disease and hormone replacement treatment. A pilot case control study. British Medical Journal, 282, 1277–1278.

    Article  Google Scholar 

  • Anderson, N. B., Williams, R. B., & Lane, J. D. (1984). Cardiovascular responses to mental arithmetic and interpersonal challenge among black female adults. Psychophysiology, 21, 568 (Abstract).

    Google Scholar 

  • Asian, S., Nelson, L., Carruthers, M., & Lader, M. (1981). Stress and age effects on catecholamines in normal subjects. Journal of Psychosomatic Research, 25, 33–41.

    Article  Google Scholar 

  • Awaritefe, A., & Kadiri, A. U. (1982). The state-trait anxiety inventory and sex. Physiology and Behavior, 29, 211–213.

    Article  PubMed  CAS  Google Scholar 

  • Bain, C., Willet, W., Hennekens, S. C., Rosner, B., Belanger, C., & Speizer, F. E. (1981). Use of postmenopausal hormones and risk of myocardial infarction. Circulation, 64, 42–46.

    Article  PubMed  CAS  Google Scholar 

  • Baldwin, S. F., & Clevenger, T. (1980). Effect of speakers’ sex and size of audience on heart rate changes during short impromptu speeches. Psychological Reports, 46, 131–134.

    Article  Google Scholar 

  • Bell, G. H., Davidson, J. N., & Scarborough, H. (1968). Textbook of physiology and biochemistry. London: Livingstone.

    Google Scholar 

  • Berkson, D. M., Stamler, J., & Cohen, D. B. (1964). Ovarian function and coronary atherosclerosis. Clinical Obstetrics and Gynecology, 7, 504–530.

    Article  Google Scholar 

  • Bush, T. L., & Barrett-Connor, E. (1985). Noncontraceptive estrogen use and cardiovascular disease. Epidemiologic Reviews, 7, 80–104.

    Google Scholar 

  • Carroll, D., Turner, J. R., Lee, H. J., & Stephenson, J. (1984). Temporal consistency of individual differences in cardiac response to a video game. Biological Psychology, 19, 81–93.

    Article  PubMed  CAS  Google Scholar 

  • Centerwall, B. A. (1981). Premenopausal hysterectomy and cardiovascular disease. American Journal of Obstetrics and Gynecology, 139, 58–61.

    PubMed  CAS  Google Scholar 

  • Collins, A., Eneroth, P., & Landgren, B. (1985). Psychoneuroendocrine stress responses and mood as related to the menstrual cycle. Psychosomatic Medicine, 47, 512–526.

    PubMed  CAS  Google Scholar 

  • Collins, A., & Frankenhaeuser, M. (1978). Stress response in male and female engineering students. Journal of Human Stress, 4, 43–48.

    Article  PubMed  CAS  Google Scholar 

  • Collins, A., Hanson, V., Eneroth, P., Hagenfeldt, K., Lundberg, U., & Frankenhaeuser, M. (1982). Psychophysiological stress responses in postmenopausal women before and after hormonal replacement therapy. Human Neu-robiology, 1, 153–159.

    CAS  Google Scholar 

  • Coronary Drug Project Research Group (1973). The Coronary Drug Project findings leading to discontinuation of the 2.5 mg/day estrogen group. Journal of the American Medical Association, 226, 652–657.

    Article  Google Scholar 

  • Cuche, J. L., Kuchel, O., Barbeau, A., & Genest, J. (1975). Sex differences in the urinary catecholamines. Endocrine Research Communications, 2, 549–559.

    PubMed  CAS  Google Scholar 

  • Dalmaz, Y., & Peyrin, L. (1982). Sex-differences in cate-cholamine metabolites in human urine during development and at adulthood. Journal of Neural Transmission, 54, 193–207.

    Article  PubMed  CAS  Google Scholar 

  • Davidson, L., Vandongen, R., Rouse, I. L., Beilin, L. J., & Tunney, A. (1984). Sex-related differences in resting stimulated plasma noradrenaline and adrenaline. Clinical Science, 67, 347–352.

    PubMed  CAS  Google Scholar 

  • Emmens, C. W., & Martin, L. (1964). Estrogens. Methods in Hormone Research, 3, 1–8.

    CAS  Google Scholar 

  • Forsman, L., & Lindblad, L. E. (1983). Effect of mental stress on baroreceptor-mediated changes in blood pressure and heart rate and on plasma catecholamines and subjective responses in healthy men and women. Psychosomatic Medicine, 45, 435–445.

    PubMed  CAS  Google Scholar 

  • Frankenhaeuser, M. (1983). The sympathetic-adrenal and pituitary adrenal response to challenge: Comparison between the sexes. In T. M. Dembroski, T. H. Schmidt, & G. Blumchen (Eds.), Biobehavioral bases of coronary heart disease (pp. 91–105). Basel: Karger.

    Google Scholar 

  • Frankenhaeuser, M., Dunne, E., & Lundberg, U. (1976). Sex differences in sympathetic-adrenal medullary reactions induced by different Stressors. Psychopharmacology, 47, 1–5.

    Article  PubMed  CAS  Google Scholar 

  • Frankenhaeuser, M., Lundberg, U., & Forsman, L. (1980). Dissociation between sympathetic-adrenal and pituitaryadrenal response to an achievement situation characterized by high controllability: Comparison between Type A and Type B males and females. Biological Psychology, 10, 79–91.

    Article  PubMed  CAS  Google Scholar 

  • Frankenhaeuser, M., von Wright, M. J., Collins, A., von Wright, J., Sedvall, G., & Swahn, C. G. (1978). Sex differences in psychoendocrine reactions to examination stress. Psychosomatic Medicine, 40, 334–343.

    PubMed  CAS  Google Scholar 

  • Freedman, R. R., Sabharwal, S. C., & Desai, N. (1987). Sex differences in peripheral vascular adrenergic receptors. Circulation Research, 61, 581–585.

    Article  PubMed  CAS  Google Scholar 

  • Frey, M. A., & Siervogel, R. M. (1983). Cardiovascular response to a mentally stressful stimulus. Japan Heart Journal, 24, 315–323.

    Article  CAS  Google Scholar 

  • Gackenbach, J. (1982). Collegiate swimmers: Sex differences in self-reports and indices of physiological stress. Perceptual and Motor Skills, 55, 555–558.

    Article  PubMed  CAS  Google Scholar 

  • Garrett, K. F., & Elder, S. T. (1984). The menstrual cycle from a bio-behavioral approach: A comparison of oral contraceptive and non-contraceptive users. International Journal of Psychophysiology, 1, 209–214.

    Article  PubMed  CAS  Google Scholar 

  • Gasul, B. M., Arcilla, R. A., & Lev, M. (Eds.). (1966). Heart disease in children: Diagnosis and treatment. Philadelphia: Lippincott.

    Google Scholar 

  • Goldstein, D. S., Levinson, P., & Keiser, H. R. (1983). Plasma and urinary catecholamines during the human ovulatory cycle. American Journal of Obstetrics, 146, 824–829.

    CAS  Google Scholar 

  • Graham, L. A., Cohen, S. I., & Shavonian, B. M. (1966). Sex differences in autonomic responses during instrumental conditioning. Psychosomatic Medicine, 28, 264–271.

    PubMed  CAS  Google Scholar 

  • Hastrup, J. L., Kraemer, D. L., & Phillips, S. M. (1986, October). Blood pressure and heart rate of women under 45 with total hysterectomy: Effects and stress and family history of hypertension. Presentation at the annual meeting of the Society for Psychophysiological Research, Montreal.

    Google Scholar 

  • Hastrup, J. L., & Light, K. C. (1984). Sex differences in cardiovascular stress responses: Modulation as a function of menstrual cycle phases. Journal of Psychosomatic Research, 28, 475–483.

    Article  PubMed  CAS  Google Scholar 

  • Hjortland, M. C., McNamara, P. M., & Kannel, W. B. (1976). Some atherogenic concomitants of menopause: The Framingham study. American Journal of Epidemiology, 103, 304–311.

    PubMed  CAS  Google Scholar 

  • Holmes, D. S., Solomon, S., & Rump, B. S. (1982). Cardiac and subjective response to cognitive challenge and to controlled physical exercise by male and female coronary prone (Type A) and noncoronary prone persons. Journal of Psychosomatic Research, 26, 309–316.

    Article  PubMed  CAS  Google Scholar 

  • Houston, B. K. (1986). Psychological variables and cardiovascular and neuroendocrine reactivity. In K. A. Matthews, S. M. Weiss, T. Detre, T. M. Dembroski, B. Falkner, S. B. Manuck, & R. B. Williams, Jr. (Eds.), Handbook of stress, reactivity, and cardiovascular disease (pp. 207–230). New York: Wiley.

    Google Scholar 

  • Jick, H., Dinan, B., & Rothman, K. J. (1978). Oral contraceptive, and nonfatal myocardial infarction. Journal of the American Medical Association, 239, 1403–1406.

    Article  PubMed  CAS  Google Scholar 

  • Johansson, G. (1972). Sex differences in the catecholamine output of children. Acta Physiologica Scandinavia, 85, 569–572.

    Article  CAS  Google Scholar 

  • Johansson, G., Frankenhaeuser, M., & Magnussen, J. (1973). Catecholamine output in school children as related to performance and adjustment. Scandinavian Journal of Psychology, 14, 20–28.

    Article  PubMed  CAS  Google Scholar 

  • Johansson, G., & Post, B. (1974). Catecholamine output of males and females over a year period. Acta Physiologica Scandinavia, 92, 557–565.

    Article  CAS  Google Scholar 

  • Jorgensen, R. S., & Houston, B. K. (1981). Family history of hypertension, gender, and cardiovascular reactivity and stereotypy during stress. Journal of Behavioral Medicine, 4, 175–189.

    Article  PubMed  CAS  Google Scholar 

  • Kannel, W. B., Hjortland, M. C., McNamara, P. M., & Gordon, T. (1976). Menopause and risk of cardiovascular disease. Annals of Internal Medicine, 85, 447–452.

    Article  PubMed  CAS  Google Scholar 

  • Klaiber, E. L., Broverman, D. M., Haffajee, L. I., Hochman, J. S., Sacks, G. M., & Dalen, D. J. E. (1982). Serum estrogen levels in men with acute myocardial infarction. American Medical Journal, 73, 872–880.

    Article  CAS  Google Scholar 

  • Krantz, D. S., & Manuck, S. B. (1984). Acute psychophysiological reactivity and risk of cardiovascular disease: A review and methodologic critique. Psychological Bulletin, 96, 435–464.

    Article  PubMed  CAS  Google Scholar 

  • Ladisich, W. (1977). Influence of progesterone on serotonin metabolism: A possible causal factor for mood changes. Psy-choneuroendocrinology, 2, 257–266.

    Article  CAS  Google Scholar 

  • Lamprecht, L., Matta, R. J., Little, B., & Zahn, T. P. (1974). Plasma dopamine-beta-hydroxylase (DBH) activity during the menstrual cycle. Psychosomatic Medicine, 36, 304–310.

    PubMed  CAS  Google Scholar 

  • Lane, J. D., White, A. D., & Williams, R. B., Jr. (1984). Cardiovascular effects of mental arithmetic in Type A and Type B females. Psychophysiology, 21, 39–46.

    Article  PubMed  CAS  Google Scholar 

  • Lawler, K. A., Allen, M. T., Critcher, E. C., & Standard, B. A. (1981). The relationship of physiological responses to coronary-prone behavior pattern in children. Journal of Behavioral Medicine, 4, 203–216.

    Article  PubMed  CAS  Google Scholar 

  • Lawler, K. A., Rixse, A., & Allen, M. T. (1983). Type A behavior and psychophysiological responses in adult women. Psychophysiology, 20, 343–350.

    Article  PubMed  CAS  Google Scholar 

  • Lawler, K. A., & Schmied, L. A. (1986). Cardiovascular responsivity, Type A behavior and parental history of heart disease in young women. Psychophysiology, 23, 28–32.

    Article  PubMed  CAS  Google Scholar 

  • Lawler, K. A., Schmied, L., Mitchell, V. P., & Rixse, A. (1984). Type A behavior and physiological responsivity in young women. Journal of Psychosomatic Research, 28, 197–204.

    Article  PubMed  CAS  Google Scholar 

  • Lenney, E. (1977). Women’s self-confidence in achievement settings. Psychological Bulletin, 84, 1–13.

    Article  Google Scholar 

  • Liberson, C. W., & Liberson, W. T. (1975). Sex differences in autonomic responses to electric shock. Psychophysiology, 12, 182–186.

    Article  PubMed  CAS  Google Scholar 

  • Little, B. C., & Zahn, T. P. (1974). Changes in mood and autonomic functioning during menstrual cycle. Psychophysiology, 11, 579–590.

    Article  PubMed  CAS  Google Scholar 

  • Lobo, R., Shoupe, D., Roy, S., & Wellington, P. (1984). Central and peripheral metabolites of norepinephrine and dopamine in postmenopausal women. American Journal of Obstetrics and Gynecology, 149, 548–552.

    PubMed  CAS  Google Scholar 

  • Lucisano, A. A., Campora, M. E., Russo, N., Maniccia, E., Montemurro, A., & Dell’Acqua, S. (1984). Ovarian and peripheral plasma levels of progestins, androgens and estrogens in post-menopausal women. Maturitas, 6, 45–53.

    Article  PubMed  CAS  Google Scholar 

  • Lundberg, E., & Frankenhaeuser, M. (1980). Pituitary-adrenal and sympathetic-adrenal correlates of distress and effort. Journal of Psychosomatic Research, 24, 125–130.

    Article  PubMed  CAS  Google Scholar 

  • MacDougall, J. M., Dembroski, T. M., & Krantz, D. S. (1981). Effects of types of challenge on pressor and heart rate responses in Type A and B women. Psychophysiology, 18, 1–9.

    Article  PubMed  CAS  Google Scholar 

  • Mann, J. I., & Inman, W. H. W. (1975). Oral contraceptives and death from myocardial infarction. British Medical Journal, 2, 245–248.

    Article  PubMed  CAS  Google Scholar 

  • Mann, J. I., Inman, W. H. W., & Thorogood, M. (1976). Oral contraceptive use in older women and fatal myocardial infarction. British Medical Journal, 2, 445–449.

    Article  PubMed  CAS  Google Scholar 

  • Manuck, S. B., Craft, S., & Gold, K. J. (1978). Coronaryprone behavior pattern and cardiovascular response. Psychophysiology, 15, 403–411.

    Article  PubMed  CAS  Google Scholar 

  • Marinan, K. T., Leshner, A. I., & Doyle, M. P. (1976). Menstrual cycle status and adrenocortical reactivity to psychological stress. Psychoneuroendocrinology, 1, 213–218.

    Article  Google Scholar 

  • Matthews, K. A. (1982). Psychological perspectives on the Type A behavioral pattern. Psychological Bulletin, 91, 293–323.

    Article  PubMed  CAS  Google Scholar 

  • Matthews, K. A., Weiss, S. M., Detre, T., Dembroski, T. M., Falkner, B., Manuck, S. B., & Williams, R. B., Jr. (Eds.). (1986). Handbook of stress, reactivity and cardiovascular disease. New York: Wiley.

    Google Scholar 

  • McConathy, W. J., & Alaupovic, P. (1981). Effects of estrogens on the plasma lipoprotein system in menopausal and postmenopausal women. In R. M. Greenshalgh (Ed.), Hormones and vascular disease (pp. 319–330). London: Pitman Press.

    Google Scholar 

  • Myrstern, A. L., Lundberg, U., Frankenhaeuser, M., Ryan, G., Dolphin, C., & Cullen, J. (1984). Sex-role orientation as related to psychological and physiological responses during achievement and orthostatic stress. Motivation and Emotion, 8, 243–258.

    Article  Google Scholar 

  • National Center for Health Statistics (1977). Blood pressure levels of persons 6-74 years of age. United States 1971-1974. Vital and Health Statistics, 11, 203.

    Google Scholar 

  • Neus, H., & von Eiff, A. W. (1985). Selected topics in the methodology of stress testing: Time course, gender and adaptation. In A. Steptoe, H. Ruddel, & H. Neus (Eds.), Clinical and methodological issues in cardiovascular psychophysiology (pp. 78–92). Berlin: Springer-Verlag.

    Chapter  Google Scholar 

  • Patkai, P., Johansson, G., & Post, B. (1974). Mood alertness and sympathetic-adrenal medullary activity during the menstrual cycle. Psychosomatic Medicine, 36, 503–512.

    PubMed  CAS  Google Scholar 

  • Phillips, G. B. (1978). Sex, hormones, risk factors and carii.

    Google Scholar 

  • Polefrone, J. M., & Manuck, S. B. (1988). Effects of menstrual phase and parental history of hypertension on cardiovascular response to cognitive challenge. Psychosomatic Medicine, 50, 23–36.

    PubMed  CAS  Google Scholar 

  • Prosser, C. L. (1973). Comparative animal physiology (3rd ed.). Philadelphia: Saunders.

    Google Scholar 

  • Rauste-von Wright, M., von Wright, J., & Frankenhaeuser, M. (1981). Relationships between sex-related psychological characteristics during adolescence and catecholamine excretion during achievement stress. Psychophysiology, 18, 362–370.

    Article  PubMed  CAS  Google Scholar 

  • Rosenberg, L., Armstrong, B., & Jick, H. (1976). Myocardial infarction and estrogen therapy in post-menopausal women. New England Journal of Medicine, 294, 1256–1259.

    Article  PubMed  CAS  Google Scholar 

  • Royal College of General Practioners’ Oral Contraception Study (1981). Further analyses of mortality in oral contraceptive users. Lancet, 1, 541–546.

    Google Scholar 

  • Saab, P. G., Matthews, K. A., Stoney, C. M., McDonald, R. H. (in press). Premenopausal and postmenopausal women differ in their cardiovascular and neuroendocrine responses to behavioral Stressors. Psychophysiology.

    Google Scholar 

  • Schlaadt, R. G., & Shannon, P. T. (1986). Drugs of choice. Englewood Cliffs, NJ: Prentice-Hall.

    Google Scholar 

  • Stamfer, M. J., Willett, W. C., Colditz, G. A., Rosner, B., Speizer, F. E., & Hennekens, C. H. (1985). A prospective study of postmenopausal estrogen therapy and coronary heart disease. The New England Journal of Medicine, 313, 1044–1049.

    Article  Google Scholar 

  • Stamler, J. (1975). Epidemiology of hypertension: Achievements and challenges. In M. Moser (Ed.), Hypertension: A practical approach (pp. 1–43). Boston: Little, Brown.

    Google Scholar 

  • Stern, M. P., Brown, B. W., Haskell, W. L.; Farquhar, J. W., Wehrle, C. L., & Wood, D. S. (1976). Cardiovascular risk and use of estrogens or estrogen/progesteron combinations. Journal of the American Medical Association, 235, 811–815.

    Article  PubMed  CAS  Google Scholar 

  • Stoney, C. M., Langer, A. W., & Gelling, P. D. (1986). The effects of menstrual cycle phase on cardiovascular and pulmonary responses to behavioral and exercise stress. Psychology, 23, 393–402.

    CAS  Google Scholar 

  • Stout, R. (1982). Hormones and atherosclerosis. Lancaster: MTP Press.

    Book  Google Scholar 

  • Tennes, K., & Kreye, M. (1985). Children’s adrenocortical responses to classroom activities and tests in elementary school. Psychosomatic Medicine, 47, 451–460.

    PubMed  CAS  Google Scholar 

  • Tracy, R. E. (1966). Sex difference in coronary disease: Two opposing views. Journal of Chronic Diseases, 19, 1245–1251.

    Article  PubMed  CAS  Google Scholar 

  • Van Egeren, L. F. (1979). Cardiovascular changes during social competition in a mixed motive game. Journal of Personality and Social Psychology, 37, 858–864.

    Article  PubMed  Google Scholar 

  • Vermeulen, A. (1976). The hormonal activity of the post menopausal ovary. Journal of Clinical Endocrinology and Metabolism, 42, 247–253.

    Article  PubMed  CAS  Google Scholar 

  • Vessey, M., Doll, R., Peto, R., Johnson, B., & Wiggins, P. (1976). A long-term-follow-up study of women using different methods of contraception—An interim report. Journal of Biosocial Sciences, 8, 373–427.

    Article  CAS  Google Scholar 

  • von Eiff, A. W., Plotz, E. J., Beck, K. J., & Czernik, A. (1971). The effect of estrogens and progestins on blood pressure regulation of normotensive women. American Journal of Obstetrics and Gynecology, 109, 887–892.

    Google Scholar 

  • Wasilewska, E., Kobus, E., & Bargiel, Z. (1980). Urinary catecholamine excretion and plasma dopamine-beta-hydrox-ylase activity in mental work performed in two periods of menstrual cycle in women. In E. Usdin, R. Kvetansky, & I. J. Kopin (Eds.), Stress and catecholamines: Recent advances (pp. 549–554). Amsterdam: Elsevier/North-Holland.

    Google Scholar 

  • Williams, R. B., Lane, J. D., Kuhn, C. M., Melosh, W., White, A. R., & Schanberg, S. M. (1982). Type A behavior and elevated physiological and neuroendocrine response to cognitive tasks. Science, 218, 483–485.

    Article  PubMed  Google Scholar 

  • Wren, B. G., & Routledge, A. D. (1981). Blood pressure changes: Oestrogens in climacteric women. Medical Journal of Australia, 2, 528–531.

    PubMed  CAS  Google Scholar 

  • Zacur, H. A., Tyson, J. E., Ziegler, M. G., & Lake, C. R. (1978). Plasma dopamine-β-hydroxylase activity and nor-epinephrine levels during the human menstrual cycle. American Journal of Obstetrics and Gynecology, 130, 148–151.

    CAS  Google Scholar 

  • Zuspan, F. P., & Zuspan, K. J. (1973). Ovulatory plasma amine (epinephrine and norepinephrine) surge in the woman. American Journal of Obstetrics and Gynecology, 117, 654–660.

    PubMed  CAS  Google Scholar 

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Saab, P.G. (1989). Cardiovascular and Neuroendocrine Responses to Challenge in Males and Females. In: Schneiderman, N., Weiss, S.M., Kaufmann, P.G. (eds) Handbook of Research Methods in Cardiovascular Behavioral Medicine. The Springer Series in Behavioral Psychophysiology and Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0906-0_29

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