Pyridoxine in the Long-Term Follow-Up of Crystalluric Stone Formers
The excretion of oxalic acid in the urine is significantly higher in calcium-oxalate stone formers than in healthy control subjects (1). Patients with primary hyperoxaluria also have a raised excretion of urinary oxalate. Some cases of primary hyperoxaluria respond to high doses of pyridoxine with a fall in urinary oxalate excretion to normal levels (2). The magnitude of calcium oxalate crystalluria is directly proportional to the oxalate concentration in the urine (3). This study was undertaken to determine the effect of pyridoxine on calcium oxalate crystalluria.
KeywordsOxalate Pyridoxine Monohydrate Dihydrate
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