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Urolithiasis pp 831-832 | Cite as

Calcium Oxalate Stone Therapy with Thiazides and Allopurinol: A Five-Year Study

  • K. Jarrar
  • V. Graef
  • R. H. Boedeker

Abstract

Thirty-five patients (20–60 years of age) suffering from calcium oxalate urolithiasis were observed for a five-year period while being treated with thiazide diuretics and allopurinol. In order to examine the effects of such treatment modalities on both clinical and biochemical parameters in serum and urine, and on stone frequency, these patients were divided into two groups:
  1. a)

    patients demonstrating normocalciuria and hyperuricosuria (n=18) were treated with allopurinol (300 mg/day);

     
  2. b)

    patients demonstrating hypercalciuria and hyperuricosuria (n=17) were treated with thiazides (50 mg/day), potassium (16 mmol/day), and allopurinol (300 mg/day).

     

Keywords

Uric Acid Urinary Excretion Serum Uric Acid Uric Acid Level Calcium Oxalate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • K. Jarrar
    • 1
    • 2
  • V. Graef
    • 1
    • 2
  • R. H. Boedeker
    • 1
    • 2
  1. 1.Department of UrologyUniversity of GiessenGiessenGermany
  2. 2.Institute of ChemistryUniversity of GiessenGiessenGermany

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